Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events: Individual patient data meta-analysis

A. Meijer, H. J. Conradi, E. H. Bos, M. Anselmino, R. M. Carney, J. Denollet, F. Doyle, K. E. Freedland, S. L. Grace, S. H. Hosseini, D. A. Lane, L. Pilote, K. Parakh, C. Rafanelli, H. Sato, R. P. Steeds, C. Welin, P. De Jonge

Research output: Contribution to journalArticle

Abstract

Background: The association between depression after myocardial infarction and increased risk of mortality and cardiac morbidity may be due to cardiac disease severity. Aims: To combine original data from studies on the association between post-infarction depression and prognosis into one database, and to investigate to what extent such depression predicts prognosis independently of disease severity. Method: An individual patient data meta-analysis of studies was conducted using multilevel, multivariable Cox regression analyses. Results: Sixteen studies participated, creating a database of 10 175 post-infarction cases. Hazard ratios for post-infarction depression were 1.32 (95% CI 1.26-1.38, P

Original languageEnglish (US)
Pages (from-to)90-102
Number of pages13
JournalBritish Journal of Psychiatry
Volume203
Issue number2
DOIs
StatePublished - Aug 2013

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Infarction
Meta-Analysis
Myocardial Infarction
Mortality
Databases
Heart Diseases
Regression Analysis
Morbidity

ASJC Scopus subject areas

  • Psychiatry and Mental health

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Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events : Individual patient data meta-analysis. / Meijer, A.; Conradi, H. J.; Bos, E. H.; Anselmino, M.; Carney, R. M.; Denollet, J.; Doyle, F.; Freedland, K. E.; Grace, S. L.; Hosseini, S. H.; Lane, D. A.; Pilote, L.; Parakh, K.; Rafanelli, C.; Sato, H.; Steeds, R. P.; Welin, C.; De Jonge, P.

In: British Journal of Psychiatry, Vol. 203, No. 2, 08.2013, p. 90-102.

Research output: Contribution to journalArticle

Meijer, A, Conradi, HJ, Bos, EH, Anselmino, M, Carney, RM, Denollet, J, Doyle, F, Freedland, KE, Grace, SL, Hosseini, SH, Lane, DA, Pilote, L, Parakh, K, Rafanelli, C, Sato, H, Steeds, RP, Welin, C & De Jonge, P 2013, 'Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events: Individual patient data meta-analysis', British Journal of Psychiatry, vol. 203, no. 2, pp. 90-102. https://doi.org/10.1192/bjp.bp.112.111195
Meijer, A. ; Conradi, H. J. ; Bos, E. H. ; Anselmino, M. ; Carney, R. M. ; Denollet, J. ; Doyle, F. ; Freedland, K. E. ; Grace, S. L. ; Hosseini, S. H. ; Lane, D. A. ; Pilote, L. ; Parakh, K. ; Rafanelli, C. ; Sato, H. ; Steeds, R. P. ; Welin, C. ; De Jonge, P. / Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events : Individual patient data meta-analysis. In: British Journal of Psychiatry. 2013 ; Vol. 203, No. 2. pp. 90-102.
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T2 - Individual patient data meta-analysis

AU - Meijer, A.

AU - Conradi, H. J.

AU - Bos, E. H.

AU - Anselmino, M.

AU - Carney, R. M.

AU - Denollet, J.

AU - Doyle, F.

AU - Freedland, K. E.

AU - Grace, S. L.

AU - Hosseini, S. H.

AU - Lane, D. A.

AU - Pilote, L.

AU - Parakh, K.

AU - Rafanelli, C.

AU - Sato, H.

AU - Steeds, R. P.

AU - Welin, C.

AU - De Jonge, P.

PY - 2013/8

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