TY - JOUR
T1 - Adjunctive antibacterial agents as a salvage therapy in relapsed vascular pythiosis patients
AU - Susaengrat, Nuttapon
AU - Torvorapanit, Pattama
AU - Plongla, Rongpong
AU - Chuleerarux, Nipat
AU - Manothummetha, Kasama
AU - Tuangsirisup, Jarruprot
AU - Worasilchai, Navaporn
AU - Chindamporn, Ariya
AU - Permpalung, Nitipong
N1 - Publisher Copyright:
© 2019 The Author(s)
PY - 2019/11
Y1 - 2019/11
N2 - Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy. We report two novel cases of intra-abdominal pythiosis in patients for whom surgery could not be performed, who were successfully treated with adjunctive antibacterial agents.
AB - Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy. We report two novel cases of intra-abdominal pythiosis in patients for whom surgery could not be performed, who were successfully treated with adjunctive antibacterial agents.
KW - Azithromycin
KW - Clarithromycin
KW - Doxycycline
KW - Vascular pythiosis
KW - Voriconazole
UR - http://www.scopus.com/inward/record.url?scp=85072660717&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85072660717&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2019.08.032
DO - 10.1016/j.ijid.2019.08.032
M3 - Article
C2 - 31493524
AN - SCOPUS:85072660717
SN - 1201-9712
VL - 88
SP - 27
EP - 30
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
ER -