Adipokines in obesity

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Adipose tissue is the source of soluble mediators (adipokines), secreted mainly by adipocytes. Leptin acts on the brain and peripheral organs to regulate energy homeostasis and the neuroendocrine axis. Adiponectin regulates glucose and lipid metabolism by targeting the liver and skeletal muscle. Adiposederived proinflammatory cytokines, vasoactive peptides, coagulation and complement factors, visfatin, vaspin and retinol-binding protein signal through paracrine and hormonal mechanisms. Understanding the biology of adipose tissue and the rapidly growing list of adipokines provides new insights into normal physiological regulation, as well as the pathogenesis and treatment of obesity, diabetes and disorders of lipid metabolism and cardiovascular system.

Original languageEnglish (US)
Title of host publicationObesity and Metabolism
Pages182-197
Number of pages16
Volume36
DOIs
StatePublished - 2007
Externally publishedYes

Publication series

NameFrontiers of Hormone Research
Volume36
ISSN (Print)03013073

Fingerprint

Adipokines
Adipose Tissue
Obesity
Lipid Metabolism Disorders
Nicotinamide Phosphoribosyltransferase
Retinol-Binding Proteins
Blood Coagulation Factors
Adiponectin
Cardiovascular System
Leptin
Lipid Metabolism
Adipocytes
Skeletal Muscle
Homeostasis
Cytokines
Glucose
Peptides
Liver
Brain

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Ahima, R. S., & Osei, S. (2007). Adipokines in obesity. In Obesity and Metabolism (Vol. 36, pp. 182-197). (Frontiers of Hormone Research; Vol. 36). https://doi.org/10.1159/000115365

Adipokines in obesity. / Ahima, Rexford S; Osei, S.

Obesity and Metabolism. Vol. 36 2007. p. 182-197 (Frontiers of Hormone Research; Vol. 36).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ahima, RS & Osei, S 2007, Adipokines in obesity. in Obesity and Metabolism. vol. 36, Frontiers of Hormone Research, vol. 36, pp. 182-197. https://doi.org/10.1159/000115365
Ahima RS, Osei S. Adipokines in obesity. In Obesity and Metabolism. Vol. 36. 2007. p. 182-197. (Frontiers of Hormone Research). https://doi.org/10.1159/000115365
Ahima, Rexford S ; Osei, S. / Adipokines in obesity. Obesity and Metabolism. Vol. 36 2007. pp. 182-197 (Frontiers of Hormone Research).
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