Adherence to pharmacological interventions

Current trends and future directions

Shellie Ellis, Sally Shumaker, William Sieber, Cynthia S Rand, Roger Anderson, Mary Benes-Malone, Stuart Cohen, Gail Crowley, Beth Dugan, Jacqueline Dunbar-Jacob, Deborah Farmer, Betty Kreuziger, Janet Lawrence, Wendy McBee, Paige McDonald, Carol Murphy, Linda Nyquist, Marcia Ory, Christin De La Paz, Mary Ann Sevick & 4 others Melissa Swaim, Perla Vargas, Kathleen Weeks, Linda Wieclaw

Research output: Contribution to journalArticle

Abstract

The complexity of adherence to pharmacological interventions is frequently underestimated. Consequently, little research has been done to understand, improve, or evaluate the effects of adherence to drug protocols. While efforts to better measure and increase adherence require dedicated resources, improved adherence in existing clinical research can potentially cut costs in trial size and length. This paper outlines strategies to facilitate research on adherence to pharmacological interventions including: reporting of adherence data, changing how we conceptualize adherence to pharmaceuticals, understanding issues unique to older adults' pill-taking behavior, and creating standardized methodologies to measure adherence. Further, we describe some promising research areas that may lead to effective interventions: adherence 'typologies' and modality matching. Control Clin Trials 2000;21:218S-225S Copyright (C) 2000 Elsevier Science Inc.

Original languageEnglish (US)
JournalControlled Clinical Trials
Volume21
Issue number5 SUPPL. 1
StatePublished - Dec 2000

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Pharmacology
Research
Pharmaceutical Preparations
Research Design
Costs and Cost Analysis
Direction compound

Keywords

  • Clinical trials
  • Drugs
  • Geriatrics
  • Patient adherence

ASJC Scopus subject areas

  • Pharmacology

Cite this

Ellis, S., Shumaker, S., Sieber, W., Rand, C. S., Anderson, R., Benes-Malone, M., ... Wieclaw, L. (2000). Adherence to pharmacological interventions: Current trends and future directions. Controlled Clinical Trials, 21(5 SUPPL. 1).

Adherence to pharmacological interventions : Current trends and future directions. / Ellis, Shellie; Shumaker, Sally; Sieber, William; Rand, Cynthia S; Anderson, Roger; Benes-Malone, Mary; Cohen, Stuart; Crowley, Gail; Dugan, Beth; Dunbar-Jacob, Jacqueline; Farmer, Deborah; Kreuziger, Betty; Lawrence, Janet; McBee, Wendy; McDonald, Paige; Murphy, Carol; Nyquist, Linda; Ory, Marcia; De La Paz, Christin; Sevick, Mary Ann; Swaim, Melissa; Vargas, Perla; Weeks, Kathleen; Wieclaw, Linda.

In: Controlled Clinical Trials, Vol. 21, No. 5 SUPPL. 1, 12.2000.

Research output: Contribution to journalArticle

Ellis, S, Shumaker, S, Sieber, W, Rand, CS, Anderson, R, Benes-Malone, M, Cohen, S, Crowley, G, Dugan, B, Dunbar-Jacob, J, Farmer, D, Kreuziger, B, Lawrence, J, McBee, W, McDonald, P, Murphy, C, Nyquist, L, Ory, M, De La Paz, C, Sevick, MA, Swaim, M, Vargas, P, Weeks, K & Wieclaw, L 2000, 'Adherence to pharmacological interventions: Current trends and future directions', Controlled Clinical Trials, vol. 21, no. 5 SUPPL. 1.
Ellis S, Shumaker S, Sieber W, Rand CS, Anderson R, Benes-Malone M et al. Adherence to pharmacological interventions: Current trends and future directions. Controlled Clinical Trials. 2000 Dec;21(5 SUPPL. 1).
Ellis, Shellie ; Shumaker, Sally ; Sieber, William ; Rand, Cynthia S ; Anderson, Roger ; Benes-Malone, Mary ; Cohen, Stuart ; Crowley, Gail ; Dugan, Beth ; Dunbar-Jacob, Jacqueline ; Farmer, Deborah ; Kreuziger, Betty ; Lawrence, Janet ; McBee, Wendy ; McDonald, Paige ; Murphy, Carol ; Nyquist, Linda ; Ory, Marcia ; De La Paz, Christin ; Sevick, Mary Ann ; Swaim, Melissa ; Vargas, Perla ; Weeks, Kathleen ; Wieclaw, Linda. / Adherence to pharmacological interventions : Current trends and future directions. In: Controlled Clinical Trials. 2000 ; Vol. 21, No. 5 SUPPL. 1.
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