Adherence to human small intestines of capsulated Vibrio cholerae O139

Tatsuo Yamamoto; M. John Albert; R. Bradley Sack

doi:10.1111/j.1574-6968.1994.tb06893.x

Adherence to human small intestines of capsulated Vibrio cholerae O139

Tatsuo Yamamoto, M. John Albert, R. Bradley Sack

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Capsulated cells of V. cholerae O139 adhered to formalis-fixed or native mucosa of the small intestines from an adult and a child. The primary adherence target was mucus. Capsulated O139 cells adhered better to the antigen sampling cells (M cells) of ileal Peyer's patch than to the absorptive cells. O139 cells on the mucosa appeared as small aggregates. Similar organisms were found on the mucosa of duodenal biopsy samples from patients infected with V. cholerae O139. The findings indicated that capsulated cells of V. cholerae O139 tend to autoagglutinate and contribute to the effective adherence to the intestinal mucosa.

Original language	English (US)
Pages (from-to)	229-235
Number of pages	7
Journal	FEMS microbiology letters
Volume	119
Issue number	1-2
DOIs	https://doi.org/10.1111/j.1574-6968.1994.tb06893.x
State	Published - Jun 1 1994
Externally published	Yes

Keywords

Adherence
Capsule
Duodenal mucosal biopsy
Human intestines
M cell
Vibrio cholerae O139

ASJC Scopus subject areas

Microbiology
Molecular Biology
Genetics

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10.1111/j.1574-6968.1994.tb06893.x

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title = "Adherence to human small intestines of capsulated Vibrio cholerae O139",

abstract = "Capsulated cells of V. cholerae O139 adhered to formalis-fixed or native mucosa of the small intestines from an adult and a child. The primary adherence target was mucus. Capsulated O139 cells adhered better to the antigen sampling cells (M cells) of ileal Peyer's patch than to the absorptive cells. O139 cells on the mucosa appeared as small aggregates. Similar organisms were found on the mucosa of duodenal biopsy samples from patients infected with V. cholerae O139. The findings indicated that capsulated cells of V. cholerae O139 tend to autoagglutinate and contribute to the effective adherence to the intestinal mucosa.",

keywords = "Adherence, Capsule, Duodenal mucosal biopsy, Human intestines, M cell, Vibrio cholerae O139",

author = "Tatsuo Yamamoto and {John Albert}, M. and {Bradley Sack}, R.",

note = "Funding Information: We thank Yoshifumi Takeda for bacterial strains, helpful discussion,a nd encouragement. This work was supportedb y a grant-in-aidfo r scientific researchf rom the Ministry of Education, Science, and Culture, and a grant from Departmenot f Health and Welfare of Japan.",

year = "1994",

month = jun,

day = "1",

doi = "10.1111/j.1574-6968.1994.tb06893.x",

language = "English (US)",

volume = "119",

pages = "229--235",

journal = "FEMS microbiology letters",

issn = "0378-1097",

publisher = "Wiley-Blackwell",

number = "1-2",

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TY - JOUR

T1 - Adherence to human small intestines of capsulated Vibrio cholerae O139

AU - Yamamoto, Tatsuo

AU - John Albert, M.

AU - Bradley Sack, R.

N1 - Funding Information: We thank Yoshifumi Takeda for bacterial strains, helpful discussion,a nd encouragement. This work was supportedb y a grant-in-aidfo r scientific researchf rom the Ministry of Education, Science, and Culture, and a grant from Departmenot f Health and Welfare of Japan.

PY - 1994/6/1

Y1 - 1994/6/1

N2 - Capsulated cells of V. cholerae O139 adhered to formalis-fixed or native mucosa of the small intestines from an adult and a child. The primary adherence target was mucus. Capsulated O139 cells adhered better to the antigen sampling cells (M cells) of ileal Peyer's patch than to the absorptive cells. O139 cells on the mucosa appeared as small aggregates. Similar organisms were found on the mucosa of duodenal biopsy samples from patients infected with V. cholerae O139. The findings indicated that capsulated cells of V. cholerae O139 tend to autoagglutinate and contribute to the effective adherence to the intestinal mucosa.

AB - Capsulated cells of V. cholerae O139 adhered to formalis-fixed or native mucosa of the small intestines from an adult and a child. The primary adherence target was mucus. Capsulated O139 cells adhered better to the antigen sampling cells (M cells) of ileal Peyer's patch than to the absorptive cells. O139 cells on the mucosa appeared as small aggregates. Similar organisms were found on the mucosa of duodenal biopsy samples from patients infected with V. cholerae O139. The findings indicated that capsulated cells of V. cholerae O139 tend to autoagglutinate and contribute to the effective adherence to the intestinal mucosa.

KW - Adherence

KW - Capsule

KW - Duodenal mucosal biopsy

KW - Human intestines

KW - M cell

KW - Vibrio cholerae O139

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DO - 10.1111/j.1574-6968.1994.tb06893.x

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SN - 0378-1097

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ER -

Adherence to human small intestines of capsulated Vibrio cholerae O139

Abstract

Keywords

ASJC Scopus subject areas

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