Adherence issues related to sublingual immunotherapy as perceived by allergists

Silvia Scurati, Franco Frati, Gianni Passalacqua, Paola Puccinelli, Cecile Hilaire, Cristoforo Incorvaia, Gennaro D'Avino, Rosa Comi, Mario Lo Schiavo, Francesco Pezzuto, Carmen Montera, Antonio Pio, Maria Teresa Ielpo, Francesco Cellini, Licia Vicentini, Roberto Pecorari, Tiziana Aresu, Lucetta Capra, Elena De Benedictis, Claudio BombiDaniela Zauli, Annarita Vanzi, Carlo Alberto Paltrinieri, Alfeo Bondioli, Isabella Paletta, Domenica Ventura, Francesco Mei, Franco Paolini, Caterina Colangelo, Enrico Cavallucci, Francesco Cucinelli, Rosanna Tinari, Giuseppe Ermini, Valerio Beltrami, Elio Novembre, Cinzia Begliomini, Erminia Marchese, Enrico Solito, Valentino Ammannati, Gaetanino Molino, Elena Galli, Mauro Baldassini, Loreta Di Michele, Mauro Calvani, Mirella Gidaro, Alberto Venuti, Enrico Li Bianchi, Fulvio Benassi, Donatella Pocobelli, Paola Zangari, Maria Grazia De Rocco, Antonella Lo Vecchio, Giuseppe Pingitore, Orazio Grimaldi, Domenico Schiavino, Nicola Perrone, Maria Antonietta Frieri, Valerio Di Rienzo, Salvatore Tripodi, Alessandro Scarpa, Mirala Tomsic, Roberta Bonaguro, Gian Enrico Senna, Alberto Sirena, Franca Turatello, Stefano Crescioli, Elisabetta Favero, Lucia Billeri, Fulvia Chieco Bianchi, Carla Gemignani, Mario Zanforlin, Maria Angiola Crivellaro, Birgir Hendrick, Adriana Maltauro, Simonetta Masieri, Maria Elisabetta Conte, Mario Fama, Marcella Pozzan, Patrizia Bonadonna, Stefania Casanova, Elisabetta Vallerani, Michele Schiappoli, Franco Borghesan, Giuseppina Giro, Stefano Casotto, Loredana Berardino, Giovanna Zanoni, Renato Ariano, Riccardo Aquilina, Renato Pellegrino, Pietro Marsico, Angelica Del Giudice, Giuseppe Narzisi, Valerio Tomaselli, Gianfranco Fornaca, Mauro Favro, Bruna Loperfido, Cesare Gallo, Sebastiano Buffoni, Federica Gani, Paolo Raviolo, Stefano Faggionato, Tiziana Truffelli, Livio Vivalda, Monica Albano, Renato Enzo Rossi, Giovanni Lattuada, Fausto Bona, Luisella Quaglio, Adriana Chiesa, Marco Trapani, Rosalba Seminara, Beniamino Cucchi, Silvana Oderda, Giovanni Borio, Giuseppe Galeasso, Paolo Garbaccio, Antonino De Marco, Fulvia Marengo, Gianni Cadario, Silvia Manzoni, Claudio Vinay, Antonio Curcio, Alberto Silvestri, Antonella Peduto, Gian Galeazzo Riario-Sforza, Anna Maria Forgnone, Piercarlo Barocelli, Nicoletta Tartaglia, Gianfranco Feyles, Adriana Giacone, Vittorio Ricca, Giuseppe Guida, Franco Nebiolo, Luisa Bommarito, Enrico Heffler, Felice Vietti, Maurizio Galimberti, Eleonora Savi, Antonio Pappacoda, Paolo Bottero, Stefania Porcu, Giuseppe Felice, Daniele Berra, Maria Francesca Spina, Valerio Pravettoni, Ambra M. Calamari, Elena Varin, Enrico Iemoli, Daniele Lietti, Daniele Ghiglioni, Alessandro Fiocchi, Anna Tosi, Mariangela Poppa, Antonio Caviglia, Massimo Restuccia, Marina Russello, Paolo Alciato, Giuseppina Manzotti, Emanuela Ranghino, Giorgio Luraschi, Andrea Rapetti, Federica Rivolta, Flavio Allegri, Luigi Terracciano, Fabio Agostinis, Pier Paolo Piras, Giuseppe Ronchi, Giulio Gaspardini, Vincenzo Caria, Fortunato Tolu, Dina Fantasia, Paola Carta, Anna Moraschini, Roberto Quilleri, Antonietta Santelli, Paolo Prandini, Giorgia Del Giudice, Aldo Apollonio, Lucio Bonazza, Maria Teresa Franzini, Silvia Branchi, Mario Zanca, Sandro Rinaldi, Luca Catelli, Tullio Zanoletti, Cristina Cosentino, Fabrizio Della Torre, Luigi Cremonte, Dario Musazzi, Claudia Suli, Loredana Rivolta, Anna Ottolenghi, Gianluca Marino, Giuseppe Sterza, Renato Sambugaro, Antonella Orlandini, Paola Minale, Susanna Voltolini, Donatella Bignardi, Pinuccia Omodeo, Antonio Tiri, Stefania Milani, Barbara Ronchi, Giovanna Licardi, Paola Bruni, Joseph Scibilia, Jan Schroeder, Francesca Crosti, Angela Maltagliati, Maria R. Alesina, Marisa Mosca, Gennaro Leone, Giorgio Napolitano, Giuseppe Di Gruttola, Guglielmo Scala, Silvia Mascio, Annamaria Valente, Ilaria Marchetiello, Romano Catello, Antonio Gazulli, Antonio Del Prete, Alfonso M. Varricchio, Agostino Carbone, Angelo Forestieri, Maria Stillitano, Luigi Leonetti, Enrico Tirroni, Francesco Castellano, Francesco Abbagnara, Francesco Romano, Carmelo Levanti, Marcello Cilia, Rocco Longo, Angelo Ferrari, Alberto Ferrari, Roberto Merenda, Antonio Di Ponti, Enrico Guercio, Lorenzo Surace, Giuseppe Ammendola, Francesco Tansella, Lucia Peccarisi, Lorenza Stragapede, Michele Minenna, Massimo Granato, Nicola Fuiano, Alessandro Pannofino, Simona Ciuffreda, Angela Giannotta, Giuseppe Morero, Lucia D'Oronzio, Giordano Taddeo, Eustachio Nettis, Giuseppe Cinquepalmi, Carlo Lamanna, Fulvio Mastrandrea, Mauro Minelli, Francesco Salamino, Lionello Muratore, Francesco Latorre, Carlo Quarta, Maria Ventura, Giannamaria D'Ippolito, Francesco Giannoccaro, Porzia Dambra, Luigi Pinto, Michele Triggiani, Giorgio Munno, Giacomo Manfredi, Giuseppe Lonero, Vincenzo Damiano, Giuseppe Errico, Elisabetta Di Leo, Francesco Manzari, Virgilio Spagna, Augusto Arsieni, Aurelia Matarrese, Giuseppe Mazzarella, Giovanni Scarcia, Rosa Scarano, Antonio Ferrannini, Antonio Pastore, Patrizia Maionchi, Luigi Filannino, Margherita Tria, Giampiero Giuliano, Elisabetta Damiani, Nicola Scichilone, Margherita Marchese, Anna Lucania, Mauro Marino, Luigi Strazzeri, Silvana Tumminello, Giovanni I. Vitale, Salvatore Gulotta, Giuseppe Gragotto, Marcello Zambito, Domenico Greco, Giuseppe Valenti, Giorgio Licitra, Enzo Cannata, Rosalia Filpi, Mariarita Contraffatto, Stefania Sichili, Salvatore Randazzo, Giovanna Scarantino, Bruno Lo Porto, Franco Pavone, Claudio Di Bartolo, Antonino Paternò, Francesca Rapisarda, Erasmo Laudani, Salvatore Leonardi, Vincenzo Padua, Gaetano Cabibbo, Giuseppe Marino Guzzardi, Francesco Deluca, Claudio Agozzino, Rosa Pettinato, Marco Ghini

Research output: Contribution to journalArticle

Abstract

Objectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. Methods: We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Results: Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54% of allergists), followed by the possibility of reimbursement (ranked 1 by 34%), and by the absence of side effects (ranked 1 by 21%). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20% of allergists. Conclusion: These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adherence to SLIT, and that further improvement of adherence is likely to be achieved by improving the patient information provided by prescribers.

Original languageEnglish (US)
Pages (from-to)141-145
Number of pages5
JournalPatient Preference and Adherence
Volume4
StatePublished - 2010
Externally publishedYes

Fingerprint

Sublingual Immunotherapy
Patient Compliance
supervision
questionnaire
Patient Education
costs
Immunotherapy
Meta-Analysis
Allergists
education
Asthma
Clinical Trials
Costs and Cost Analysis

Keywords

  • Adherence
  • Cost
  • Efficacy
  • Side effects
  • Sublingual immunotherapy

ASJC Scopus subject areas

  • Social Sciences (miscellaneous)
  • Medicine (miscellaneous)
  • Health Policy
  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Cite this

Scurati, S., Frati, F., Passalacqua, G., Puccinelli, P., Hilaire, C., Incorvaia, C., ... Ghini, M. (2010). Adherence issues related to sublingual immunotherapy as perceived by allergists. Patient Preference and Adherence, 4, 141-145.

Adherence issues related to sublingual immunotherapy as perceived by allergists. / Scurati, Silvia; Frati, Franco; Passalacqua, Gianni; Puccinelli, Paola; Hilaire, Cecile; Incorvaia, Cristoforo; D'Avino, Gennaro; Comi, Rosa; Lo Schiavo, Mario; Pezzuto, Francesco; Montera, Carmen; Pio, Antonio; Teresa Ielpo, Maria; Cellini, Francesco; Vicentini, Licia; Pecorari, Roberto; Aresu, Tiziana; Capra, Lucetta; De Benedictis, Elena; Bombi, Claudio; Zauli, Daniela; Vanzi, Annarita; Alberto Paltrinieri, Carlo; Bondioli, Alfeo; Paletta, Isabella; Ventura, Domenica; Mei, Francesco; Paolini, Franco; Colangelo, Caterina; Cavallucci, Enrico; Cucinelli, Francesco; Tinari, Rosanna; Ermini, Giuseppe; Beltrami, Valerio; Novembre, Elio; Begliomini, Cinzia; Marchese, Erminia; Solito, Enrico; Ammannati, Valentino; Molino, Gaetanino; Galli, Elena; Baldassini, Mauro; Di Michele, Loreta; Calvani, Mauro; Gidaro, Mirella; Venuti, Alberto; Li Bianchi, Enrico; Benassi, Fulvio; Pocobelli, Donatella; Zangari, Paola; De Rocco, Maria Grazia; Lo Vecchio, Antonella; Pingitore, Giuseppe; Grimaldi, Orazio; Schiavino, Domenico; Perrone, Nicola; Antonietta Frieri, Maria; Di Rienzo, Valerio; Tripodi, Salvatore; Scarpa, Alessandro; Tomsic, Mirala; Bonaguro, Roberta; Enrico Senna, Gian; Sirena, Alberto; Turatello, Franca; Crescioli, Stefano; Favero, Elisabetta; Billeri, Lucia; Chieco Bianchi, Fulvia; Gemignani, Carla; Zanforlin, Mario; Angiola Crivellaro, Maria; Hendrick, Birgir; Maltauro, Adriana; Masieri, Simonetta; Elisabetta Conte, Maria; Fama, Mario; Pozzan, Marcella; Bonadonna, Patrizia; Casanova, Stefania; Vallerani, Elisabetta; Schiappoli, Michele; Borghesan, Franco; Giro, Giuseppina; Casotto, Stefano; Berardino, Loredana; Zanoni, Giovanna; Ariano, Renato; Aquilina, Riccardo; Pellegrino, Renato; Marsico, Pietro; Del Giudice, Angelica; Narzisi, Giuseppe; Tomaselli, Valerio; Fornaca, Gianfranco; Favro, Mauro; Loperfido, Bruna; Gallo, Cesare; Buffoni, Sebastiano; Gani, Federica; Raviolo, Paolo; Faggionato, Stefano; Truffelli, Tiziana; Vivalda, Livio; Albano, Monica; Enzo Rossi, Renato; Lattuada, Giovanni; Bona, Fausto; Quaglio, Luisella; Chiesa, Adriana; Trapani, Marco; Seminara, Rosalba; Cucchi, Beniamino; Oderda, Silvana; Borio, Giovanni; Galeasso, Giuseppe; Garbaccio, Paolo; De Marco, Antonino; Marengo, Fulvia; Cadario, Gianni; Manzoni, Silvia; Vinay, Claudio; Curcio, Antonio; Silvestri, Alberto; Peduto, Antonella; Riario-Sforza, Gian Galeazzo; Maria Forgnone, Anna; Barocelli, Piercarlo; Tartaglia, Nicoletta; Feyles, Gianfranco; Giacone, Adriana; Ricca, Vittorio; Guida, Giuseppe; Nebiolo, Franco; Bommarito, Luisa; Heffler, Enrico; Vietti, Felice; Galimberti, Maurizio; Savi, Eleonora; Pappacoda, Antonio; Bottero, Paolo; Porcu, Stefania; Felice, Giuseppe; Berra, Daniele; Francesca Spina, Maria; Pravettoni, Valerio; Calamari, Ambra M.; Varin, Elena; Iemoli, Enrico; Lietti, Daniele; Ghiglioni, Daniele; Fiocchi, Alessandro; Tosi, Anna; Poppa, Mariangela; Caviglia, Antonio; Restuccia, Massimo; Russello, Marina; Alciato, Paolo; Manzotti, Giuseppina; Ranghino, Emanuela; Luraschi, Giorgio; Rapetti, Andrea; Rivolta, Federica; Allegri, Flavio; Terracciano, Luigi; Agostinis, Fabio; Paolo Piras, Pier; Ronchi, Giuseppe; Gaspardini, Giulio; Caria, Vincenzo; Tolu, Fortunato; Fantasia, Dina; Carta, Paola; Moraschini, Anna; Quilleri, Roberto; Santelli, Antonietta; Prandini, Paolo; Del Giudice, Giorgia; Apollonio, Aldo; Bonazza, Lucio; Teresa Franzini, Maria; Branchi, Silvia; Zanca, Mario; Rinaldi, Sandro; Catelli, Luca; Zanoletti, Tullio; Cosentino, Cristina; Della Torre, Fabrizio; Cremonte, Luigi; Musazzi, Dario; Suli, Claudia; Rivolta, Loredana; Ottolenghi, Anna; Marino, Gianluca; Sterza, Giuseppe; Sambugaro, Renato; Orlandini, Antonella; Minale, Paola; Voltolini, Susanna; Bignardi, Donatella; Omodeo, Pinuccia; Tiri, Antonio; Milani, Stefania; Ronchi, Barbara; Licardi, Giovanna; Bruni, Paola; Scibilia, Joseph; Schroeder, Jan; Crosti, Francesca; Maltagliati, Angela; Alesina, Maria R.; Mosca, Marisa; Leone, Gennaro; Napolitano, Giorgio; Di Gruttola, Giuseppe; Scala, Guglielmo; Mascio, Silvia; Valente, Annamaria; Marchetiello, Ilaria; Catello, Romano; Gazulli, Antonio; Del Prete, Antonio; Varricchio, Alfonso M.; Carbone, Agostino; Forestieri, Angelo; Stillitano, Maria; Leonetti, Luigi; Tirroni, Enrico; Castellano, Francesco; Abbagnara, Francesco; Romano, Francesco; Levanti, Carmelo; Cilia, Marcello; Longo, Rocco; Ferrari, Angelo; Ferrari, Alberto; Merenda, Roberto; Di Ponti, Antonio; Guercio, Enrico; Surace, Lorenzo; Ammendola, Giuseppe; Tansella, Francesco; Peccarisi, Lucia; Stragapede, Lorenza; Minenna, Michele; Granato, Massimo; Fuiano, Nicola; Pannofino, Alessandro; Ciuffreda, Simona; Giannotta, Angela; Morero, Giuseppe; D'Oronzio, Lucia; Taddeo, Giordano; Nettis, Eustachio; Cinquepalmi, Giuseppe; Lamanna, Carlo; Mastrandrea, Fulvio; Minelli, Mauro; Salamino, Francesco; Muratore, Lionello; Latorre, Francesco; Quarta, Carlo; Ventura, Maria; D'Ippolito, Giannamaria; Giannoccaro, Francesco; Dambra, Porzia; Pinto, Luigi; Triggiani, Michele; Munno, Giorgio; Manfredi, Giacomo; Lonero, Giuseppe; Damiano, Vincenzo; Errico, Giuseppe; Di Leo, Elisabetta; Manzari, Francesco; Spagna, Virgilio; Arsieni, Augusto; Matarrese, Aurelia; Mazzarella, Giuseppe; Scarcia, Giovanni; Scarano, Rosa; Ferrannini, Antonio; Pastore, Antonio; Maionchi, Patrizia; Filannino, Luigi; Tria, Margherita; Giuliano, Giampiero; Damiani, Elisabetta; Scichilone, Nicola; Marchese, Margherita; Lucania, Anna; Marino, Mauro; Strazzeri, Luigi; Tumminello, Silvana; Vitale, Giovanni I.; Gulotta, Salvatore; Gragotto, Giuseppe; Zambito, Marcello; Greco, Domenico; Valenti, Giuseppe; Licitra, Giorgio; Cannata, Enzo; Filpi, Rosalia; Contraffatto, Mariarita; Sichili, Stefania; Randazzo, Salvatore; Scarantino, Giovanna; Lo Porto, Bruno; Pavone, Franco; Di Bartolo, Claudio; Paternò, Antonino; Rapisarda, Francesca; Laudani, Erasmo; Leonardi, Salvatore; Padua, Vincenzo; Cabibbo, Gaetano; Marino Guzzardi, Giuseppe; Deluca, Francesco; Agozzino, Claudio; Pettinato, Rosa; Ghini, Marco.

In: Patient Preference and Adherence, Vol. 4, 2010, p. 141-145.

Research output: Contribution to journalArticle

Scurati, S, Frati, F, Passalacqua, G, Puccinelli, P, Hilaire, C, Incorvaia, C, D'Avino, G, Comi, R, Lo Schiavo, M, Pezzuto, F, Montera, C, Pio, A, Teresa Ielpo, M, Cellini, F, Vicentini, L, Pecorari, R, Aresu, T, Capra, L, De Benedictis, E, Bombi, C, Zauli, D, Vanzi, A, Alberto Paltrinieri, C, Bondioli, A, Paletta, I, Ventura, D, Mei, F, Paolini, F, Colangelo, C, Cavallucci, E, Cucinelli, F, Tinari, R, Ermini, G, Beltrami, V, Novembre, E, Begliomini, C, Marchese, E, Solito, E, Ammannati, V, Molino, G, Galli, E, Baldassini, M, Di Michele, L, Calvani, M, Gidaro, M, Venuti, A, Li Bianchi, E, Benassi, F, Pocobelli, D, Zangari, P, De Rocco, MG, Lo Vecchio, A, Pingitore, G, Grimaldi, O, Schiavino, D, Perrone, N, Antonietta Frieri, M, Di Rienzo, V, Tripodi, S, Scarpa, A, Tomsic, M, Bonaguro, R, Enrico Senna, G, Sirena, A, Turatello, F, Crescioli, S, Favero, E, Billeri, L, Chieco Bianchi, F, Gemignani, C, Zanforlin, M, Angiola Crivellaro, M, Hendrick, B, Maltauro, A, Masieri, S, Elisabetta Conte, M, Fama, M, Pozzan, M, Bonadonna, P, Casanova, S, Vallerani, E, Schiappoli, M, Borghesan, F, Giro, G, Casotto, S, Berardino, L, Zanoni, G, Ariano, R, Aquilina, R, Pellegrino, R, Marsico, P, Del Giudice, A, Narzisi, G, Tomaselli, V, Fornaca, G, Favro, M, Loperfido, B, Gallo, C, Buffoni, S, Gani, F, Raviolo, P, Faggionato, S, Truffelli, T, Vivalda, L, Albano, M, Enzo Rossi, R, Lattuada, G, Bona, F, Quaglio, L, Chiesa, A, Trapani, M, Seminara, R, Cucchi, B, Oderda, S, Borio, G, Galeasso, G, Garbaccio, P, De Marco, A, Marengo, F, Cadario, G, Manzoni, S, Vinay, C, Curcio, A, Silvestri, A, Peduto, A, Riario-Sforza, GG, Maria Forgnone, A, Barocelli, P, Tartaglia, N, Feyles, G, Giacone, A, Ricca, V, Guida, G, Nebiolo, F, Bommarito, L, Heffler, E, Vietti, F, Galimberti, M, Savi, E, Pappacoda, A, Bottero, P, Porcu, S, Felice, G, Berra, D, Francesca Spina, M, Pravettoni, V, Calamari, AM, Varin, E, Iemoli, E, Lietti, D, Ghiglioni, D, Fiocchi, A, Tosi, A, Poppa, M, Caviglia, A, Restuccia, M, Russello, M, Alciato, P, Manzotti, G, Ranghino, E, Luraschi, G, Rapetti, A, Rivolta, F, Allegri, F, Terracciano, L, Agostinis, F, Paolo Piras, P, Ronchi, G, Gaspardini, G, Caria, V, Tolu, F, Fantasia, D, Carta, P, Moraschini, A, Quilleri, R, Santelli, A, Prandini, P, Del Giudice, G, Apollonio, A, Bonazza, L, Teresa Franzini, M, Branchi, S, Zanca, M, Rinaldi, S, Catelli, L, Zanoletti, T, Cosentino, C, Della Torre, F, Cremonte, L, Musazzi, D, Suli, C, Rivolta, L, Ottolenghi, A, Marino, G, Sterza, G, Sambugaro, R, Orlandini, A, Minale, P, Voltolini, S, Bignardi, D, Omodeo, P, Tiri, A, Milani, S, Ronchi, B, Licardi, G, Bruni, P, Scibilia, J, Schroeder, J, Crosti, F, Maltagliati, A, Alesina, MR, Mosca, M, Leone, G, Napolitano, G, Di Gruttola, G, Scala, G, Mascio, S, Valente, A, Marchetiello, I, Catello, R, Gazulli, A, Del Prete, A, Varricchio, AM, Carbone, A, Forestieri, A, Stillitano, M, Leonetti, L, Tirroni, E, Castellano, F, Abbagnara, F, Romano, F, Levanti, C, Cilia, M, Longo, R, Ferrari, A, Ferrari, A, Merenda, R, Di Ponti, A, Guercio, E, Surace, L, Ammendola, G, Tansella, F, Peccarisi, L, Stragapede, L, Minenna, M, Granato, M, Fuiano, N, Pannofino, A, Ciuffreda, S, Giannotta, A, Morero, G, D'Oronzio, L, Taddeo, G, Nettis, E, Cinquepalmi, G, Lamanna, C, Mastrandrea, F, Minelli, M, Salamino, F, Muratore, L, Latorre, F, Quarta, C, Ventura, M, D'Ippolito, G, Giannoccaro, F, Dambra, P, Pinto, L, Triggiani, M, Munno, G, Manfredi, G, Lonero, G, Damiano, V, Errico, G, Di Leo, E, Manzari, F, Spagna, V, Arsieni, A, Matarrese, A, Mazzarella, G, Scarcia, G, Scarano, R, Ferrannini, A, Pastore, A, Maionchi, P, Filannino, L, Tria, M, Giuliano, G, Damiani, E, Scichilone, N, Marchese, M, Lucania, A, Marino, M, Strazzeri, L, Tumminello, S, Vitale, GI, Gulotta, S, Gragotto, G, Zambito, M, Greco, D, Valenti, G, Licitra, G, Cannata, E, Filpi, R, Contraffatto, M, Sichili, S, Randazzo, S, Scarantino, G, Lo Porto, B, Pavone, F, Di Bartolo, C, Paternò, A, Rapisarda, F, Laudani, E, Leonardi, S, Padua, V, Cabibbo, G, Marino Guzzardi, G, Deluca, F, Agozzino, C, Pettinato, R & Ghini, M 2010, 'Adherence issues related to sublingual immunotherapy as perceived by allergists', Patient Preference and Adherence, vol. 4, pp. 141-145.
Scurati S, Frati F, Passalacqua G, Puccinelli P, Hilaire C, Incorvaia C et al. Adherence issues related to sublingual immunotherapy as perceived by allergists. Patient Preference and Adherence. 2010;4:141-145.
Scurati, Silvia ; Frati, Franco ; Passalacqua, Gianni ; Puccinelli, Paola ; Hilaire, Cecile ; Incorvaia, Cristoforo ; D'Avino, Gennaro ; Comi, Rosa ; Lo Schiavo, Mario ; Pezzuto, Francesco ; Montera, Carmen ; Pio, Antonio ; Teresa Ielpo, Maria ; Cellini, Francesco ; Vicentini, Licia ; Pecorari, Roberto ; Aresu, Tiziana ; Capra, Lucetta ; De Benedictis, Elena ; Bombi, Claudio ; Zauli, Daniela ; Vanzi, Annarita ; Alberto Paltrinieri, Carlo ; Bondioli, Alfeo ; Paletta, Isabella ; Ventura, Domenica ; Mei, Francesco ; Paolini, Franco ; Colangelo, Caterina ; Cavallucci, Enrico ; Cucinelli, Francesco ; Tinari, Rosanna ; Ermini, Giuseppe ; Beltrami, Valerio ; Novembre, Elio ; Begliomini, Cinzia ; Marchese, Erminia ; Solito, Enrico ; Ammannati, Valentino ; Molino, Gaetanino ; Galli, Elena ; Baldassini, Mauro ; Di Michele, Loreta ; Calvani, Mauro ; Gidaro, Mirella ; Venuti, Alberto ; Li Bianchi, Enrico ; Benassi, Fulvio ; Pocobelli, Donatella ; Zangari, Paola ; De Rocco, Maria Grazia ; Lo Vecchio, Antonella ; Pingitore, Giuseppe ; Grimaldi, Orazio ; Schiavino, Domenico ; Perrone, Nicola ; Antonietta Frieri, Maria ; Di Rienzo, Valerio ; Tripodi, Salvatore ; Scarpa, Alessandro ; Tomsic, Mirala ; Bonaguro, Roberta ; Enrico Senna, Gian ; Sirena, Alberto ; Turatello, Franca ; Crescioli, Stefano ; Favero, Elisabetta ; Billeri, Lucia ; Chieco Bianchi, Fulvia ; Gemignani, Carla ; Zanforlin, Mario ; Angiola Crivellaro, Maria ; Hendrick, Birgir ; Maltauro, Adriana ; Masieri, Simonetta ; Elisabetta Conte, Maria ; Fama, Mario ; Pozzan, Marcella ; Bonadonna, Patrizia ; Casanova, Stefania ; Vallerani, Elisabetta ; Schiappoli, Michele ; Borghesan, Franco ; Giro, Giuseppina ; Casotto, Stefano ; Berardino, Loredana ; Zanoni, Giovanna ; Ariano, Renato ; Aquilina, Riccardo ; Pellegrino, Renato ; Marsico, Pietro ; Del Giudice, Angelica ; Narzisi, Giuseppe ; Tomaselli, Valerio ; Fornaca, Gianfranco ; Favro, Mauro ; Loperfido, Bruna ; Gallo, Cesare ; Buffoni, Sebastiano ; Gani, Federica ; Raviolo, Paolo ; Faggionato, Stefano ; Truffelli, Tiziana ; Vivalda, Livio ; Albano, Monica ; Enzo Rossi, Renato ; Lattuada, Giovanni ; Bona, Fausto ; Quaglio, Luisella ; Chiesa, Adriana ; Trapani, Marco ; Seminara, Rosalba ; Cucchi, Beniamino ; Oderda, Silvana ; Borio, Giovanni ; Galeasso, Giuseppe ; Garbaccio, Paolo ; De Marco, Antonino ; Marengo, Fulvia ; Cadario, Gianni ; Manzoni, Silvia ; Vinay, Claudio ; Curcio, Antonio ; Silvestri, Alberto ; Peduto, Antonella ; Riario-Sforza, Gian Galeazzo ; Maria Forgnone, Anna ; Barocelli, Piercarlo ; Tartaglia, Nicoletta ; Feyles, Gianfranco ; Giacone, Adriana ; Ricca, Vittorio ; Guida, Giuseppe ; Nebiolo, Franco ; Bommarito, Luisa ; Heffler, Enrico ; Vietti, Felice ; Galimberti, Maurizio ; Savi, Eleonora ; Pappacoda, Antonio ; Bottero, Paolo ; Porcu, Stefania ; Felice, Giuseppe ; Berra, Daniele ; Francesca Spina, Maria ; Pravettoni, Valerio ; Calamari, Ambra M. ; Varin, Elena ; Iemoli, Enrico ; Lietti, Daniele ; Ghiglioni, Daniele ; Fiocchi, Alessandro ; Tosi, Anna ; Poppa, Mariangela ; Caviglia, Antonio ; Restuccia, Massimo ; Russello, Marina ; Alciato, Paolo ; Manzotti, Giuseppina ; Ranghino, Emanuela ; Luraschi, Giorgio ; Rapetti, Andrea ; Rivolta, Federica ; Allegri, Flavio ; Terracciano, Luigi ; Agostinis, Fabio ; Paolo Piras, Pier ; Ronchi, Giuseppe ; Gaspardini, Giulio ; Caria, Vincenzo ; Tolu, Fortunato ; Fantasia, Dina ; Carta, Paola ; Moraschini, Anna ; Quilleri, Roberto ; Santelli, Antonietta ; Prandini, Paolo ; Del Giudice, Giorgia ; Apollonio, Aldo ; Bonazza, Lucio ; Teresa Franzini, Maria ; Branchi, Silvia ; Zanca, Mario ; Rinaldi, Sandro ; Catelli, Luca ; Zanoletti, Tullio ; Cosentino, Cristina ; Della Torre, Fabrizio ; Cremonte, Luigi ; Musazzi, Dario ; Suli, Claudia ; Rivolta, Loredana ; Ottolenghi, Anna ; Marino, Gianluca ; Sterza, Giuseppe ; Sambugaro, Renato ; Orlandini, Antonella ; Minale, Paola ; Voltolini, Susanna ; Bignardi, Donatella ; Omodeo, Pinuccia ; Tiri, Antonio ; Milani, Stefania ; Ronchi, Barbara ; Licardi, Giovanna ; Bruni, Paola ; Scibilia, Joseph ; Schroeder, Jan ; Crosti, Francesca ; Maltagliati, Angela ; Alesina, Maria R. ; Mosca, Marisa ; Leone, Gennaro ; Napolitano, Giorgio ; Di Gruttola, Giuseppe ; Scala, Guglielmo ; Mascio, Silvia ; Valente, Annamaria ; Marchetiello, Ilaria ; Catello, Romano ; Gazulli, Antonio ; Del Prete, Antonio ; Varricchio, Alfonso M. ; Carbone, Agostino ; Forestieri, Angelo ; Stillitano, Maria ; Leonetti, Luigi ; Tirroni, Enrico ; Castellano, Francesco ; Abbagnara, Francesco ; Romano, Francesco ; Levanti, Carmelo ; Cilia, Marcello ; Longo, Rocco ; Ferrari, Angelo ; Ferrari, Alberto ; Merenda, Roberto ; Di Ponti, Antonio ; Guercio, Enrico ; Surace, Lorenzo ; Ammendola, Giuseppe ; Tansella, Francesco ; Peccarisi, Lucia ; Stragapede, Lorenza ; Minenna, Michele ; Granato, Massimo ; Fuiano, Nicola ; Pannofino, Alessandro ; Ciuffreda, Simona ; Giannotta, Angela ; Morero, Giuseppe ; D'Oronzio, Lucia ; Taddeo, Giordano ; Nettis, Eustachio ; Cinquepalmi, Giuseppe ; Lamanna, Carlo ; Mastrandrea, Fulvio ; Minelli, Mauro ; Salamino, Francesco ; Muratore, Lionello ; Latorre, Francesco ; Quarta, Carlo ; Ventura, Maria ; D'Ippolito, Giannamaria ; Giannoccaro, Francesco ; Dambra, Porzia ; Pinto, Luigi ; Triggiani, Michele ; Munno, Giorgio ; Manfredi, Giacomo ; Lonero, Giuseppe ; Damiano, Vincenzo ; Errico, Giuseppe ; Di Leo, Elisabetta ; Manzari, Francesco ; Spagna, Virgilio ; Arsieni, Augusto ; Matarrese, Aurelia ; Mazzarella, Giuseppe ; Scarcia, Giovanni ; Scarano, Rosa ; Ferrannini, Antonio ; Pastore, Antonio ; Maionchi, Patrizia ; Filannino, Luigi ; Tria, Margherita ; Giuliano, Giampiero ; Damiani, Elisabetta ; Scichilone, Nicola ; Marchese, Margherita ; Lucania, Anna ; Marino, Mauro ; Strazzeri, Luigi ; Tumminello, Silvana ; Vitale, Giovanni I. ; Gulotta, Salvatore ; Gragotto, Giuseppe ; Zambito, Marcello ; Greco, Domenico ; Valenti, Giuseppe ; Licitra, Giorgio ; Cannata, Enzo ; Filpi, Rosalia ; Contraffatto, Mariarita ; Sichili, Stefania ; Randazzo, Salvatore ; Scarantino, Giovanna ; Lo Porto, Bruno ; Pavone, Franco ; Di Bartolo, Claudio ; Paternò, Antonino ; Rapisarda, Francesca ; Laudani, Erasmo ; Leonardi, Salvatore ; Padua, Vincenzo ; Cabibbo, Gaetano ; Marino Guzzardi, Giuseppe ; Deluca, Francesco ; Agozzino, Claudio ; Pettinato, Rosa ; Ghini, Marco. / Adherence issues related to sublingual immunotherapy as perceived by allergists. In: Patient Preference and Adherence. 2010 ; Vol. 4. pp. 141-145.
@article{ed125d425bcf439ead554bde741d0a3a,
title = "Adherence issues related to sublingual immunotherapy as perceived by allergists",
abstract = "Objectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. Methods: We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Results: Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54{\%} of allergists), followed by the possibility of reimbursement (ranked 1 by 34{\%}), and by the absence of side effects (ranked 1 by 21{\%}). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20{\%} of allergists. Conclusion: These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adherence to SLIT, and that further improvement of adherence is likely to be achieved by improving the patient information provided by prescribers.",
keywords = "Adherence, Cost, Efficacy, Side effects, Sublingual immunotherapy",
author = "Silvia Scurati and Franco Frati and Gianni Passalacqua and Paola Puccinelli and Cecile Hilaire and Cristoforo Incorvaia and Gennaro D'Avino and Rosa Comi and {Lo Schiavo}, Mario and Francesco Pezzuto and Carmen Montera and Antonio Pio and {Teresa Ielpo}, Maria and Francesco Cellini and Licia Vicentini and Roberto Pecorari and Tiziana Aresu and Lucetta Capra and {De Benedictis}, Elena and Claudio Bombi and Daniela Zauli and Annarita Vanzi and {Alberto Paltrinieri}, Carlo and Alfeo Bondioli and Isabella Paletta and Domenica Ventura and Francesco Mei and Franco Paolini and Caterina Colangelo and Enrico Cavallucci and Francesco Cucinelli and Rosanna Tinari and Giuseppe Ermini and Valerio Beltrami and Elio Novembre and Cinzia Begliomini and Erminia Marchese and Enrico Solito and Valentino Ammannati and Gaetanino Molino and Elena Galli and Mauro Baldassini and {Di Michele}, Loreta and Mauro Calvani and Mirella Gidaro and Alberto Venuti and {Li Bianchi}, Enrico and Fulvio Benassi and Donatella Pocobelli and Paola Zangari and {De Rocco}, {Maria Grazia} and {Lo Vecchio}, Antonella and Giuseppe Pingitore and Orazio Grimaldi and Domenico Schiavino and Nicola Perrone and {Antonietta Frieri}, Maria and {Di Rienzo}, Valerio and Salvatore Tripodi and Alessandro Scarpa and Mirala Tomsic and Roberta Bonaguro and {Enrico Senna}, Gian and Alberto Sirena and Franca Turatello and Stefano Crescioli and Elisabetta Favero and Lucia Billeri and {Chieco Bianchi}, Fulvia and Carla Gemignani and Mario Zanforlin and {Angiola Crivellaro}, Maria and Birgir Hendrick and Adriana Maltauro and Simonetta Masieri and {Elisabetta Conte}, Maria and Mario Fama and Marcella Pozzan and Patrizia Bonadonna and Stefania Casanova and Elisabetta Vallerani and Michele Schiappoli and Franco Borghesan and Giuseppina Giro and Stefano Casotto and Loredana Berardino and Giovanna Zanoni and Renato Ariano and Riccardo Aquilina and Renato Pellegrino and Pietro Marsico and {Del Giudice}, Angelica and Giuseppe Narzisi and Valerio Tomaselli and Gianfranco Fornaca and Mauro Favro and Bruna Loperfido and Cesare Gallo and Sebastiano Buffoni and Federica Gani and Paolo Raviolo and Stefano Faggionato and Tiziana Truffelli and Livio Vivalda and Monica Albano and {Enzo Rossi}, Renato and Giovanni Lattuada and Fausto Bona and Luisella Quaglio and Adriana Chiesa and Marco Trapani and Rosalba Seminara and Beniamino Cucchi and Silvana Oderda and Giovanni Borio and Giuseppe Galeasso and Paolo Garbaccio and {De Marco}, Antonino and Fulvia Marengo and Gianni Cadario and Silvia Manzoni and Claudio Vinay and Antonio Curcio and Alberto Silvestri and Antonella Peduto and Riario-Sforza, {Gian Galeazzo} and {Maria Forgnone}, Anna and Piercarlo Barocelli and Nicoletta Tartaglia and Gianfranco Feyles and Adriana Giacone and Vittorio Ricca and Giuseppe Guida and Franco Nebiolo and Luisa Bommarito and Enrico Heffler and Felice Vietti and Maurizio Galimberti and Eleonora Savi and Antonio Pappacoda and Paolo Bottero and Stefania Porcu and Giuseppe Felice and Daniele Berra and {Francesca Spina}, Maria and Valerio Pravettoni and Calamari, {Ambra M.} and Elena Varin and Enrico Iemoli and Daniele Lietti and Daniele Ghiglioni and Alessandro Fiocchi and Anna Tosi and Mariangela Poppa and Antonio Caviglia and Massimo Restuccia and Marina Russello and Paolo Alciato and Giuseppina Manzotti and Emanuela Ranghino and Giorgio Luraschi and Andrea Rapetti and Federica Rivolta and Flavio Allegri and Luigi Terracciano and Fabio Agostinis and {Paolo Piras}, Pier and Giuseppe Ronchi and Giulio Gaspardini and Vincenzo Caria and Fortunato Tolu and Dina Fantasia and Paola Carta and Anna Moraschini and Roberto Quilleri and Antonietta Santelli and Paolo Prandini and {Del Giudice}, Giorgia and Aldo Apollonio and Lucio Bonazza and {Teresa Franzini}, Maria and Silvia Branchi and Mario Zanca and Sandro Rinaldi and Luca Catelli and Tullio Zanoletti and Cristina Cosentino and {Della Torre}, Fabrizio and Luigi Cremonte and Dario Musazzi and Claudia Suli and Loredana Rivolta and Anna Ottolenghi and Gianluca Marino and Giuseppe Sterza and Renato Sambugaro and Antonella Orlandini and Paola Minale and Susanna Voltolini and Donatella Bignardi and Pinuccia Omodeo and Antonio Tiri and Stefania Milani and Barbara Ronchi and Giovanna Licardi and Paola Bruni and Joseph Scibilia and Jan Schroeder and Francesca Crosti and Angela Maltagliati and Alesina, {Maria R.} and Marisa Mosca and Gennaro Leone and Giorgio Napolitano and {Di Gruttola}, Giuseppe and Guglielmo Scala and Silvia Mascio and Annamaria Valente and Ilaria Marchetiello and Romano Catello and Antonio Gazulli and {Del Prete}, Antonio and Varricchio, {Alfonso M.} and Agostino Carbone and Angelo Forestieri and Maria Stillitano and Luigi Leonetti and Enrico Tirroni and Francesco Castellano and Francesco Abbagnara and Francesco Romano and Carmelo Levanti and Marcello Cilia and Rocco Longo and Angelo Ferrari and Alberto Ferrari and Roberto Merenda and {Di Ponti}, Antonio and Enrico Guercio and Lorenzo Surace and Giuseppe Ammendola and Francesco Tansella and Lucia Peccarisi and Lorenza Stragapede and Michele Minenna and Massimo Granato and Nicola Fuiano and Alessandro Pannofino and Simona Ciuffreda and Angela Giannotta and Giuseppe Morero and Lucia D'Oronzio and Giordano Taddeo and Eustachio Nettis and Giuseppe Cinquepalmi and Carlo Lamanna and Fulvio Mastrandrea and Mauro Minelli and Francesco Salamino and Lionello Muratore and Francesco Latorre and Carlo Quarta and Maria Ventura and Giannamaria D'Ippolito and Francesco Giannoccaro and Porzia Dambra and Luigi Pinto and Michele Triggiani and Giorgio Munno and Giacomo Manfredi and Giuseppe Lonero and Vincenzo Damiano and Giuseppe Errico and {Di Leo}, Elisabetta and Francesco Manzari and Virgilio Spagna and Augusto Arsieni and Aurelia Matarrese and Giuseppe Mazzarella and Giovanni Scarcia and Rosa Scarano and Antonio Ferrannini and Antonio Pastore and Patrizia Maionchi and Luigi Filannino and Margherita Tria and Giampiero Giuliano and Elisabetta Damiani and Nicola Scichilone and Margherita Marchese and Anna Lucania and Mauro Marino and Luigi Strazzeri and Silvana Tumminello and Vitale, {Giovanni I.} and Salvatore Gulotta and Giuseppe Gragotto and Marcello Zambito and Domenico Greco and Giuseppe Valenti and Giorgio Licitra and Enzo Cannata and Rosalia Filpi and Mariarita Contraffatto and Stefania Sichili and Salvatore Randazzo and Giovanna Scarantino and {Lo Porto}, Bruno and Franco Pavone and {Di Bartolo}, Claudio and Antonino Patern{\`o} and Francesca Rapisarda and Erasmo Laudani and Salvatore Leonardi and Vincenzo Padua and Gaetano Cabibbo and {Marino Guzzardi}, Giuseppe and Francesco Deluca and Claudio Agozzino and Rosa Pettinato and Marco Ghini",
year = "2010",
language = "English (US)",
volume = "4",
pages = "141--145",
journal = "Patient Preference and Adherence",
issn = "1177-889X",
publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Adherence issues related to sublingual immunotherapy as perceived by allergists

AU - Scurati, Silvia

AU - Frati, Franco

AU - Passalacqua, Gianni

AU - Puccinelli, Paola

AU - Hilaire, Cecile

AU - Incorvaia, Cristoforo

AU - D'Avino, Gennaro

AU - Comi, Rosa

AU - Lo Schiavo, Mario

AU - Pezzuto, Francesco

AU - Montera, Carmen

AU - Pio, Antonio

AU - Teresa Ielpo, Maria

AU - Cellini, Francesco

AU - Vicentini, Licia

AU - Pecorari, Roberto

AU - Aresu, Tiziana

AU - Capra, Lucetta

AU - De Benedictis, Elena

AU - Bombi, Claudio

AU - Zauli, Daniela

AU - Vanzi, Annarita

AU - Alberto Paltrinieri, Carlo

AU - Bondioli, Alfeo

AU - Paletta, Isabella

AU - Ventura, Domenica

AU - Mei, Francesco

AU - Paolini, Franco

AU - Colangelo, Caterina

AU - Cavallucci, Enrico

AU - Cucinelli, Francesco

AU - Tinari, Rosanna

AU - Ermini, Giuseppe

AU - Beltrami, Valerio

AU - Novembre, Elio

AU - Begliomini, Cinzia

AU - Marchese, Erminia

AU - Solito, Enrico

AU - Ammannati, Valentino

AU - Molino, Gaetanino

AU - Galli, Elena

AU - Baldassini, Mauro

AU - Di Michele, Loreta

AU - Calvani, Mauro

AU - Gidaro, Mirella

AU - Venuti, Alberto

AU - Li Bianchi, Enrico

AU - Benassi, Fulvio

AU - Pocobelli, Donatella

AU - Zangari, Paola

AU - De Rocco, Maria Grazia

AU - Lo Vecchio, Antonella

AU - Pingitore, Giuseppe

AU - Grimaldi, Orazio

AU - Schiavino, Domenico

AU - Perrone, Nicola

AU - Antonietta Frieri, Maria

AU - Di Rienzo, Valerio

AU - Tripodi, Salvatore

AU - Scarpa, Alessandro

AU - Tomsic, Mirala

AU - Bonaguro, Roberta

AU - Enrico Senna, Gian

AU - Sirena, Alberto

AU - Turatello, Franca

AU - Crescioli, Stefano

AU - Favero, Elisabetta

AU - Billeri, Lucia

AU - Chieco Bianchi, Fulvia

AU - Gemignani, Carla

AU - Zanforlin, Mario

AU - Angiola Crivellaro, Maria

AU - Hendrick, Birgir

AU - Maltauro, Adriana

AU - Masieri, Simonetta

AU - Elisabetta Conte, Maria

AU - Fama, Mario

AU - Pozzan, Marcella

AU - Bonadonna, Patrizia

AU - Casanova, Stefania

AU - Vallerani, Elisabetta

AU - Schiappoli, Michele

AU - Borghesan, Franco

AU - Giro, Giuseppina

AU - Casotto, Stefano

AU - Berardino, Loredana

AU - Zanoni, Giovanna

AU - Ariano, Renato

AU - Aquilina, Riccardo

AU - Pellegrino, Renato

AU - Marsico, Pietro

AU - Del Giudice, Angelica

AU - Narzisi, Giuseppe

AU - Tomaselli, Valerio

AU - Fornaca, Gianfranco

AU - Favro, Mauro

AU - Loperfido, Bruna

AU - Gallo, Cesare

AU - Buffoni, Sebastiano

AU - Gani, Federica

AU - Raviolo, Paolo

AU - Faggionato, Stefano

AU - Truffelli, Tiziana

AU - Vivalda, Livio

AU - Albano, Monica

AU - Enzo Rossi, Renato

AU - Lattuada, Giovanni

AU - Bona, Fausto

AU - Quaglio, Luisella

AU - Chiesa, Adriana

AU - Trapani, Marco

AU - Seminara, Rosalba

AU - Cucchi, Beniamino

AU - Oderda, Silvana

AU - Borio, Giovanni

AU - Galeasso, Giuseppe

AU - Garbaccio, Paolo

AU - De Marco, Antonino

AU - Marengo, Fulvia

AU - Cadario, Gianni

AU - Manzoni, Silvia

AU - Vinay, Claudio

AU - Curcio, Antonio

AU - Silvestri, Alberto

AU - Peduto, Antonella

AU - Riario-Sforza, Gian Galeazzo

AU - Maria Forgnone, Anna

AU - Barocelli, Piercarlo

AU - Tartaglia, Nicoletta

AU - Feyles, Gianfranco

AU - Giacone, Adriana

AU - Ricca, Vittorio

AU - Guida, Giuseppe

AU - Nebiolo, Franco

AU - Bommarito, Luisa

AU - Heffler, Enrico

AU - Vietti, Felice

AU - Galimberti, Maurizio

AU - Savi, Eleonora

AU - Pappacoda, Antonio

AU - Bottero, Paolo

AU - Porcu, Stefania

AU - Felice, Giuseppe

AU - Berra, Daniele

AU - Francesca Spina, Maria

AU - Pravettoni, Valerio

AU - Calamari, Ambra M.

AU - Varin, Elena

AU - Iemoli, Enrico

AU - Lietti, Daniele

AU - Ghiglioni, Daniele

AU - Fiocchi, Alessandro

AU - Tosi, Anna

AU - Poppa, Mariangela

AU - Caviglia, Antonio

AU - Restuccia, Massimo

AU - Russello, Marina

AU - Alciato, Paolo

AU - Manzotti, Giuseppina

AU - Ranghino, Emanuela

AU - Luraschi, Giorgio

AU - Rapetti, Andrea

AU - Rivolta, Federica

AU - Allegri, Flavio

AU - Terracciano, Luigi

AU - Agostinis, Fabio

AU - Paolo Piras, Pier

AU - Ronchi, Giuseppe

AU - Gaspardini, Giulio

AU - Caria, Vincenzo

AU - Tolu, Fortunato

AU - Fantasia, Dina

AU - Carta, Paola

AU - Moraschini, Anna

AU - Quilleri, Roberto

AU - Santelli, Antonietta

AU - Prandini, Paolo

AU - Del Giudice, Giorgia

AU - Apollonio, Aldo

AU - Bonazza, Lucio

AU - Teresa Franzini, Maria

AU - Branchi, Silvia

AU - Zanca, Mario

AU - Rinaldi, Sandro

AU - Catelli, Luca

AU - Zanoletti, Tullio

AU - Cosentino, Cristina

AU - Della Torre, Fabrizio

AU - Cremonte, Luigi

AU - Musazzi, Dario

AU - Suli, Claudia

AU - Rivolta, Loredana

AU - Ottolenghi, Anna

AU - Marino, Gianluca

AU - Sterza, Giuseppe

AU - Sambugaro, Renato

AU - Orlandini, Antonella

AU - Minale, Paola

AU - Voltolini, Susanna

AU - Bignardi, Donatella

AU - Omodeo, Pinuccia

AU - Tiri, Antonio

AU - Milani, Stefania

AU - Ronchi, Barbara

AU - Licardi, Giovanna

AU - Bruni, Paola

AU - Scibilia, Joseph

AU - Schroeder, Jan

AU - Crosti, Francesca

AU - Maltagliati, Angela

AU - Alesina, Maria R.

AU - Mosca, Marisa

AU - Leone, Gennaro

AU - Napolitano, Giorgio

AU - Di Gruttola, Giuseppe

AU - Scala, Guglielmo

AU - Mascio, Silvia

AU - Valente, Annamaria

AU - Marchetiello, Ilaria

AU - Catello, Romano

AU - Gazulli, Antonio

AU - Del Prete, Antonio

AU - Varricchio, Alfonso M.

AU - Carbone, Agostino

AU - Forestieri, Angelo

AU - Stillitano, Maria

AU - Leonetti, Luigi

AU - Tirroni, Enrico

AU - Castellano, Francesco

AU - Abbagnara, Francesco

AU - Romano, Francesco

AU - Levanti, Carmelo

AU - Cilia, Marcello

AU - Longo, Rocco

AU - Ferrari, Angelo

AU - Ferrari, Alberto

AU - Merenda, Roberto

AU - Di Ponti, Antonio

AU - Guercio, Enrico

AU - Surace, Lorenzo

AU - Ammendola, Giuseppe

AU - Tansella, Francesco

AU - Peccarisi, Lucia

AU - Stragapede, Lorenza

AU - Minenna, Michele

AU - Granato, Massimo

AU - Fuiano, Nicola

AU - Pannofino, Alessandro

AU - Ciuffreda, Simona

AU - Giannotta, Angela

AU - Morero, Giuseppe

AU - D'Oronzio, Lucia

AU - Taddeo, Giordano

AU - Nettis, Eustachio

AU - Cinquepalmi, Giuseppe

AU - Lamanna, Carlo

AU - Mastrandrea, Fulvio

AU - Minelli, Mauro

AU - Salamino, Francesco

AU - Muratore, Lionello

AU - Latorre, Francesco

AU - Quarta, Carlo

AU - Ventura, Maria

AU - D'Ippolito, Giannamaria

AU - Giannoccaro, Francesco

AU - Dambra, Porzia

AU - Pinto, Luigi

AU - Triggiani, Michele

AU - Munno, Giorgio

AU - Manfredi, Giacomo

AU - Lonero, Giuseppe

AU - Damiano, Vincenzo

AU - Errico, Giuseppe

AU - Di Leo, Elisabetta

AU - Manzari, Francesco

AU - Spagna, Virgilio

AU - Arsieni, Augusto

AU - Matarrese, Aurelia

AU - Mazzarella, Giuseppe

AU - Scarcia, Giovanni

AU - Scarano, Rosa

AU - Ferrannini, Antonio

AU - Pastore, Antonio

AU - Maionchi, Patrizia

AU - Filannino, Luigi

AU - Tria, Margherita

AU - Giuliano, Giampiero

AU - Damiani, Elisabetta

AU - Scichilone, Nicola

AU - Marchese, Margherita

AU - Lucania, Anna

AU - Marino, Mauro

AU - Strazzeri, Luigi

AU - Tumminello, Silvana

AU - Vitale, Giovanni I.

AU - Gulotta, Salvatore

AU - Gragotto, Giuseppe

AU - Zambito, Marcello

AU - Greco, Domenico

AU - Valenti, Giuseppe

AU - Licitra, Giorgio

AU - Cannata, Enzo

AU - Filpi, Rosalia

AU - Contraffatto, Mariarita

AU - Sichili, Stefania

AU - Randazzo, Salvatore

AU - Scarantino, Giovanna

AU - Lo Porto, Bruno

AU - Pavone, Franco

AU - Di Bartolo, Claudio

AU - Paternò, Antonino

AU - Rapisarda, Francesca

AU - Laudani, Erasmo

AU - Leonardi, Salvatore

AU - Padua, Vincenzo

AU - Cabibbo, Gaetano

AU - Marino Guzzardi, Giuseppe

AU - Deluca, Francesco

AU - Agozzino, Claudio

AU - Pettinato, Rosa

AU - Ghini, Marco

PY - 2010

Y1 - 2010

N2 - Objectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. Methods: We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Results: Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54% of allergists), followed by the possibility of reimbursement (ranked 1 by 34%), and by the absence of side effects (ranked 1 by 21%). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20% of allergists. Conclusion: These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adherence to SLIT, and that further improvement of adherence is likely to be achieved by improving the patient information provided by prescribers.

AB - Objectives: Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degree of patient adherence with treatment is still a concern. The objective of this study was to evaluate the perception by allergists of issues related to SLIT adherence. Methods: We performed a questionnaire-based survey of 296 Italian allergists, based on the adherence issues known from previous studies. The perception of importance of each item was assessed by a VAS scale ranging from 0 to 10. Results: Patient perception of clinical efficacy was considered the most important factor (ranked 1 by 54% of allergists), followed by the possibility of reimbursement (ranked 1 by 34%), and by the absence of side effects (ranked 1 by 21%). Patient education, regular follow-up, and ease of use of SLIT were ranked first by less than 20% of allergists. Conclusion: These findings indicate that clinical efficacy, cost, and side effects are perceived as the major issues influencing patient adherence to SLIT, and that further improvement of adherence is likely to be achieved by improving the patient information provided by prescribers.

KW - Adherence

KW - Cost

KW - Efficacy

KW - Side effects

KW - Sublingual immunotherapy

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UR - http://www.scopus.com/inward/citedby.url?scp=77954614858&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:77954614858

VL - 4

SP - 141

EP - 145

JO - Patient Preference and Adherence

JF - Patient Preference and Adherence

SN - 1177-889X

ER -