Adenyl cyclase in human platelets: Activity and responsiveness

Philip D. Zieve, William B. Greenough

Research output: Contribution to journalArticlepeer-review

62 Scopus citations


Hormonally responsive adenyl cyclase activity was measured in lysates of human platelets. Activity was stimulated by fluoride, prostaglandin E/, and glucagon; and was inhibited by thrombin, epinephrine, norepinephrine, and serotonin. The results suggest that adenosine-3/, 5/ monophosphate (cyclic AMP) may be important in the regulation of platelet adhesiveness.

Original languageEnglish (US)
Pages (from-to)462-466
Number of pages5
JournalBiochemical and Biophysical Research Communications
Issue number4
StatePublished - May 22 1969

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


Dive into the research topics of 'Adenyl cyclase in human platelets: Activity and responsiveness'. Together they form a unique fingerprint.

Cite this