Adenosine coronary vasodilation during hypoxia depends on adrenergic receptor activation

E. O. Feigl; F. Kajiya; J. Spaan; D. Kass

doi:10.1007/978-1-4615-2946-0_19

Adenosine coronary vasodilation during hypoxia depends on adrenergic receptor activation

E. O. Feigl, F. Kajiya, J. Spaan, D. Kass

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3 Scopus citations

Abstract

The adenosine hypothesis of coronary control was investigated during steady-state hypoxia by making measurements of coronary venous and epicardial well adenosine concentrations in adrenergically intact dogs and animals with α- and β-receptor blockade. The unexpected result was that a role for adenosine coronary vasodilation during hypoxia could only be found when adrenergic receptors were intact, but not during adrenergic blockade.

Original language	English (US)
Pages (from-to)	199-205
Number of pages	7
Journal	Advances in experimental medicine and biology
Volume	346
DOIs	https://doi.org/10.1007/978-1-4615-2946-0_19
State	Published - 1993
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/978-1-4615-2946-0_19

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title = "Adenosine coronary vasodilation during hypoxia depends on adrenergic receptor activation",

abstract = "The adenosine hypothesis of coronary control was investigated during steady-state hypoxia by making measurements of coronary venous and epicardial well adenosine concentrations in adrenergically intact dogs and animals with α- and β-receptor blockade. The unexpected result was that a role for adenosine coronary vasodilation during hypoxia could only be found when adrenergic receptors were intact, but not during adrenergic blockade.",

author = "Feigl, {E. O.} and F. Kajiya and J. Spaan and D. Kass",

year = "1993",

doi = "10.1007/978-1-4615-2946-0_19",

language = "English (US)",

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T1 - Adenosine coronary vasodilation during hypoxia depends on adrenergic receptor activation

AU - Feigl, E. O.

AU - Kajiya, F.

AU - Spaan, J.

AU - Kass, D.

PY - 1993

Y1 - 1993

N2 - The adenosine hypothesis of coronary control was investigated during steady-state hypoxia by making measurements of coronary venous and epicardial well adenosine concentrations in adrenergically intact dogs and animals with α- and β-receptor blockade. The unexpected result was that a role for adenosine coronary vasodilation during hypoxia could only be found when adrenergic receptors were intact, but not during adrenergic blockade.

AB - The adenosine hypothesis of coronary control was investigated during steady-state hypoxia by making measurements of coronary venous and epicardial well adenosine concentrations in adrenergically intact dogs and animals with α- and β-receptor blockade. The unexpected result was that a role for adenosine coronary vasodilation during hypoxia could only be found when adrenergic receptors were intact, but not during adrenergic blockade.

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DO - 10.1007/978-1-4615-2946-0_19

M3 - Article

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AN - SCOPUS:0027770138

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EP - 205

JO - Advances in experimental medicine and biology

JF - Advances in experimental medicine and biology

ER -

Adenosine coronary vasodilation during hypoxia depends on adrenergic receptor activation

Abstract

ASJC Scopus subject areas

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