The adenosine hypothesis of coronary control was investigated during steady-state hypoxia by making measurements of coronary venous and epicardial well adenosine concentrations in adrenergically intact dogs and animals with α- and β-receptor blockade. The unexpected result was that a role for adenosine coronary vasodilation during hypoxia could only be found when adrenergic receptors were intact, but not during adrenergic blockade.
|Original language||English (US)|
|Number of pages||7|
|Journal||Advances in experimental medicine and biology|
|State||Published - Dec 1 1993|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)