Adenocarcinoma arising within a tailgut cyst: Clinicopathological description and follow up of an unusual case

J. F. Graadt Van Roggen, K. Welvaart, A. De Roos, G. J A Offerhaus, P. C W Hogendoorn

Research output: Contribution to journalArticlepeer-review

Abstract

Full clinicopathological details and clinical follow up of a case of malignant transformation within a tailgut cyst are presented. A 43 year old woman presented with signs and symptoms of an imminent threatened abortion. Routine examination identified a coincidental, asymptomatic retrorectal/presacral mass. Following imaging studies, surgical resection was carried out and an adenocarcinoma arising within a preexistent tailgut cyst was identified by microscopy. Four years later the patient presented with neurological symptoms consistent with local recurrence of the turnout. Surgical biopsies confirmed this diagnosis and she was subsequently started on chemotherapy. She died soon after from a cause unrelated to the disease, after declining further active intervention. Differential diagnosis of such cases includes (cystic) teratoma, epidermal cyst, rectal duplication cyst, anal gland cyst and carcinoma, extension of local carcinoma, and metastatic disease. It is recommended that these lesions be completely excised when detected incidentally.

Original languageEnglish (US)
Pages (from-to)310-312
Number of pages3
JournalJournal of Clinical Pathology
Volume52
Issue number4
StatePublished - 1999
Externally publishedYes

Keywords

  • Adenocarcinoma
  • Tailgut cyst

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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