Addressing the challenges of phenotyping pediatric pulmonary vascular disease

Kara N. Goss, Allen D. Everett, Peter M. Mourani, Christopher D. Baker, Steven H. Abman

Research output: Contribution to journalReview articlepeer-review

Abstract

Pediatric pulmonary vascular disease (PVD) and pulmonary hypertension (PH) represent phenotypically and pathophysiologically diverse disease categories, contributing substantial morbidity and mortality to a complex array of pediatric conditions. Here, we review the multifactorial nature of pediatric PVD, with an emphasis on improved recognition, phenotyping, and endotyping strategies for pediatric PH. Novel tailored approaches to diagnosis and treatment in pediatric PVD, as well as the implications for long-term outcomes, are highlighted.

Original languageEnglish (US)
Pages (from-to)7-19
Number of pages13
JournalPulmonary Circulation
Volume7
Issue number1
DOIs
StatePublished - 2017

Keywords

  • Childhood
  • Long-term outcomes
  • Pulmonary hypertension
  • Registry studies

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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