TY - JOUR
T1 - Addition of the multidimensional prognostic index to the estimated glomerular filtration rate improves prediction of long-term all-cause mortality in older patients with chronic kidney disease
AU - Pilotto, Alberto
AU - Sancarlo, Daniele
AU - Aucella, Filippo
AU - Fontana, Andrea
AU - Addante, Filomena
AU - Copetti, Massimiliano
AU - Panza, Francesco
AU - Strippoli, Giovanni F M
AU - Ferrucci, Luigi
PY - 2012/2/1
Y1 - 2012/2/1
N2 - Current prognostic scores of chronic kidney disease (CKD) are not accurate in older patients. The aim of this study was to evaluate the prognostic accuracy of the Multidimensional Prognostic Index (MPI) in comparison with and in addition to the estimated glomerular filtration rate (eGFR) to predict long-term all-cause mortality in hospitalized older patients with CKD. In a prospective cohort study with a mean follow-up of 2 years, we calculated eGFR according to the Modification of Diet in Renal Disease study and collected information on functional, cognitive, nutritional, co-morbidities, drug use, and co-habitation status to calculate the MPI on 1,198 patients aged ≥65 years with a diagnosis of CKD from an hospital-based sample. The all-cause mortality incidence rate for 100 person-years was 18.3 (men 22.7 vs. women 15.3, p
AB - Current prognostic scores of chronic kidney disease (CKD) are not accurate in older patients. The aim of this study was to evaluate the prognostic accuracy of the Multidimensional Prognostic Index (MPI) in comparison with and in addition to the estimated glomerular filtration rate (eGFR) to predict long-term all-cause mortality in hospitalized older patients with CKD. In a prospective cohort study with a mean follow-up of 2 years, we calculated eGFR according to the Modification of Diet in Renal Disease study and collected information on functional, cognitive, nutritional, co-morbidities, drug use, and co-habitation status to calculate the MPI on 1,198 patients aged ≥65 years with a diagnosis of CKD from an hospital-based sample. The all-cause mortality incidence rate for 100 person-years was 18.3 (men 22.7 vs. women 15.3, p
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U2 - 10.1089/rej.2011.1210
DO - 10.1089/rej.2011.1210
M3 - Article
C2 - 22352434
AN - SCOPUS:84857272703
SN - 1549-1684
VL - 15
SP - 82
EP - 88
JO - Rejuvenation Research
JF - Rejuvenation Research
IS - 1
ER -