Abstract
Background and Purpose - The failure of recent trials to show the effectiveness of acute endovascular stroke therapy (EST) may be because of inadequate patient selection. We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection. Methods - We retrospectively identified patients with large-vessel occlusion considered for EST from January 2008 to August 2012. Patients before April 30, 2010, were selected based on computed tomography/computed tomography angiography (prehyperacute protocol), whereas patients on or after April 30, 2010, were selected based on computed tomography/computed tomography angiography and MRI (hyperacute MRI protocol). Demographic, clinical features, and outcomes were collected. Univariate and multivariate analyses were performed. Results - We identified 267 patients: 88 patients in prehyperacute MRI period and 179 in hyperacute MRI period. Fewer patients evaluated in the hyperacute MRI period received EST (85 of 88, 96.6% versus 92 of 179, 51.7%; P
| Original language | English (US) |
|---|---|
| Pages (from-to) | 467-472 |
| Number of pages | 6 |
| Journal | Stroke |
| Volume | 45 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2014 |
| Externally published | Yes |
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Keywords
- Cerebral revascularization
- Magnetic resonance imaging
- Stroke
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Clinical Neurology
- Advanced and Specialized Nursing
Cite this
Addition of hyperacute MRI aids in patient selection, decreasing the use of endovascular stroke therapy. / Wisco, Dolora; Uchino, Ken; Saqqur, Maher; Gebel, James M.; Aoki, Junya; Alam, Shazia; George, Pravin; Newey, Christopher R.; Man, Shumei; Tateishi, Yohei; McNeil, Julie; Winfield, Michelle; Cheng-Ching, Esteban; Hui, Ferdinand; Toth, Gabor; Bain, Mark; Rasmussen, Peter A.; Masaryk, Thomas; Ruggieri, Paul; Hussain, Muhammad Shazam.
In: Stroke, Vol. 45, No. 2, 02.2014, p. 467-472.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Addition of hyperacute MRI aids in patient selection, decreasing the use of endovascular stroke therapy
AU - Wisco, Dolora
AU - Uchino, Ken
AU - Saqqur, Maher
AU - Gebel, James M.
AU - Aoki, Junya
AU - Alam, Shazia
AU - George, Pravin
AU - Newey, Christopher R.
AU - Man, Shumei
AU - Tateishi, Yohei
AU - McNeil, Julie
AU - Winfield, Michelle
AU - Cheng-Ching, Esteban
AU - Hui, Ferdinand
AU - Toth, Gabor
AU - Bain, Mark
AU - Rasmussen, Peter A.
AU - Masaryk, Thomas
AU - Ruggieri, Paul
AU - Hussain, Muhammad Shazam
PY - 2014/2
Y1 - 2014/2
N2 - Background and Purpose - The failure of recent trials to show the effectiveness of acute endovascular stroke therapy (EST) may be because of inadequate patient selection. We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection. Methods - We retrospectively identified patients with large-vessel occlusion considered for EST from January 2008 to August 2012. Patients before April 30, 2010, were selected based on computed tomography/computed tomography angiography (prehyperacute protocol), whereas patients on or after April 30, 2010, were selected based on computed tomography/computed tomography angiography and MRI (hyperacute MRI protocol). Demographic, clinical features, and outcomes were collected. Univariate and multivariate analyses were performed. Results - We identified 267 patients: 88 patients in prehyperacute MRI period and 179 in hyperacute MRI period. Fewer patients evaluated in the hyperacute MRI period received EST (85 of 88, 96.6% versus 92 of 179, 51.7%; P
AB - Background and Purpose - The failure of recent trials to show the effectiveness of acute endovascular stroke therapy (EST) may be because of inadequate patient selection. We implemented a protocol to perform pretreatment MRI on patients with large-vessel occlusion eligible for EST to aid in patient selection. Methods - We retrospectively identified patients with large-vessel occlusion considered for EST from January 2008 to August 2012. Patients before April 30, 2010, were selected based on computed tomography/computed tomography angiography (prehyperacute protocol), whereas patients on or after April 30, 2010, were selected based on computed tomography/computed tomography angiography and MRI (hyperacute MRI protocol). Demographic, clinical features, and outcomes were collected. Univariate and multivariate analyses were performed. Results - We identified 267 patients: 88 patients in prehyperacute MRI period and 179 in hyperacute MRI period. Fewer patients evaluated in the hyperacute MRI period received EST (85 of 88, 96.6% versus 92 of 179, 51.7%; P
KW - Cerebral revascularization
KW - Magnetic resonance imaging
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=84893742576&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893742576&partnerID=8YFLogxK
U2 - 10.1161/STROKEAHA.113.003880
DO - 10.1161/STROKEAHA.113.003880
M3 - Article
C2 - 24407952
AN - SCOPUS:84893742576
VL - 45
SP - 467
EP - 472
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 2
ER -