Adaptive resistance to anti-PD1 therapy by tim-3 upregulation is mediated by the PI3k-akt pathway in head and neck cancer

Medicine & Life Sciences

• Head and Neck Neoplasms 100%
• Tumor-Infiltrating Lymphocytes 91%
• Up-Regulation 71%
• S 6 24%
• Inositol 20%
• Squamous Cell Carcinoma of Head and Neck 20%
• Therapeutics 16%
• Phosphotransferases 14%
• Immunoglobulin Domains 11%
• Neoplasms 11%
• Mucins 9%
• Tumor Microenvironment 9%
• Protein Domains 9%
• Cellular Immunity 8%
• Immunotherapy 7%
• Phosphorylation 6%
• Cytokines 5%
• T-Lymphocytes 5%
• Phenotype 5%