Adaptive-mesh-based algorithm for fluorescence molecular tomography using an analytical solution

Daifa Wang, Xiaolei Song, Jing Bai

Research output: Contribution to journalArticle

Abstract

Fluorescence molecular tomography (FMT) has become an important method for in-vivo imaging of small animals. It has been widely used for tumor genesis, cancer detection, metastasis, drug discovery, and gene therapy. In this study, an algorithm for FMT is proposed to obtain accurate and fast reconstruction by combining an adaptive mesh refinement technique and an analytical solution of diffusion equation. Numerical studies have been performed on a parallel plate FMT system with matching fluid. The reconstructions obtained show that the algorithm is efficient in computation time, and they also maintain image quality.

Original languageEnglish (US)
Pages (from-to)9722-9730
Number of pages9
JournalOptics Express
Volume15
Issue number15
DOIs
StatePublished - Jul 23 2007

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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