Acute Sixth Nerve Palsy and Retinal Hemorrhages as the Presenting Features of Acute Lymphoblastic Leukemia

Malek A. Alrobaian, Maria Adelita Vizcaino, Amanda D. Henderson

Research output: Contribution to journalArticlepeer-review

Abstract

ABSTRACT: A 36-year-old apparently healthy man presented with acute onset of diplopia. Examination demonstrated left sixth nerve palsy with 3 retinal hemorrhages noted in one eye. Gadolinium-enhanced high-resolution skull base MRI revealed left sixth nerve enhancement involving the cisternal segment. Complete blood count, cerebrospinal fluid analysis, bone marrow biopsy, and flow cytometry confirmed acute T-cell lymphoblastic leukemia with central nervous system involvement. This case demonstrates the value of high-resolution MRI in the evaluation of cranial nerve palsy in young adults and also emphasizes the importance of systemic work up in these cases, particularly when retinal findings are present.

Original languageEnglish (US)
Pages (from-to)e131-e133
JournalJournal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
Volume41
Issue number1
DOIs
StatePublished - Mar 1 2021

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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