Acute Retinal Necrosis Neuropathy: Clinical Profile and Surgical Therapy

Robert C. Sergott, Thomas M. Bosley, Peter J. Savino, Rajiv Anand, Jonathan B. Belmont, David H. Fischer

Research output: Contribution to journalArticlepeer-review

Abstract

Twelve patients (17 eyes) with the acute retinal necrosis syndrome were analyzed with special reference to the development of an acute optic neuropathy. Six patients (9 eyes) without acute optic nerve involvement were treated with intravenous acyclovir sodium and/or vitreoretinal surgery (group 1). Six patients (8 eyes) fulfilling absolute and relative criteria for acute retinal necrosis optic neuropathy were treated with intravenous acyclovir as well as optic nerve sheath decompression, and, in addition, some of these patients also underwent vitreoretinal surgery. Despite more pronounced initial visual loss compared with group 1, six eyes in group 2 regained visual acuity of 20/400 or better. In contrast, only 2 of 9 eyes in group 1 maintained their entry level visual acuity, and the visual acuities of the remaining 7 eyes deteriorated to counting fingers or worse. Therefore, the acute optic neuropathy complicating the acute retinal necrosis syndrome appears to benefit from prompt recognition and surgical decompression of the intraorbital optic nerve meninges in conjunction with intravenous acyclovir.

Original languageEnglish (US)
Pages (from-to)692-696
Number of pages5
JournalArchives of ophthalmology
Volume107
Issue number5
DOIs
StatePublished - May 1989
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Acute Retinal Necrosis Neuropathy: Clinical Profile and Surgical Therapy'. Together they form a unique fingerprint.

Cite this