Acute renal failure from multiple myeloma precipitated by ACE inhibitors.

H. Rabb, H. Gunasekaran, S. Gunasekaran, S. R. Saba

Research output: Contribution to journalArticlepeer-review

Abstract

Renal failure in multiple myeloma can be precipitated during hemodynamic perturbances of renal blood flow, as seen secondary to volume depletion, radiocontrast dye, and nonsteroidal anti-inflammatory agents. We report two cases of acute renal failure that developed suddenly after initiation of angiotensin-converting enzyme (ACE) inhibitor, both with biopsy-proven cast nephropathy. ACE inhibitors may contribute to the intratubular light chain cast formation and acute "myeloma kidney" in susceptible patients.

Original languageEnglish (US)
Pages (from-to)E5
JournalAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
Volume33
Issue number2
StatePublished - Feb 1999
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology

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