Acute pancreatitis following adult liver transplantation: A systematic review

Ahmet Danalioʇlu, Oscar Jl Mitchell, Vikesh K. Singh, Ahmet Nasuh Danalioʇlu, Hakan Şentürk, Andrew M. Cameron, Ahmet Gürakar

Research output: Contribution to journalReview articlepeer-review

Abstract

Although uncommon, acute pancreatitis is a well-recognized, but generally serious, complication following liver transplantation. In addition to being more prevalent in patients who underwent liver transplantation than in the general population, it has a more aggressive course and can be responsible for significant morbidity and mortality. The post-liver transplant population has altered anatomy, increased comorbidities, and requires a myriad of drugs. These characteristics make them different from the pre-transplant population. Despite their retrospective nature, prior studies have identified numerous etiological factors that are associated with an increased risk of acute pancreatitis following liver transplantation. These can be broadly classified into the following four categories: surgical and anatomical factors, infections, post-transplant management, and post-transplant complications. The aim of this systematic review is to assimilate the available information regarding acute pancreatitis following adult liver transplantation to describe the risk factors and natural history of the disease and to highlight possible areas for further investigation.

Original languageEnglish (US)
Pages (from-to)450-455
Number of pages6
JournalTurkish Journal of Gastroenterology
Volume26
Issue number6
DOIs
StatePublished - Nov 2015

Keywords

  • Acute pancreatitis
  • Post liver transplantation
  • Systematic review

ASJC Scopus subject areas

  • Gastroenterology

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