Acute oral toxicity of butyl nitrite

Ronald W. Wood; Christopher Cox

doi:10.1002/jat.2550010108

Acute oral toxicity of butyl nitrite

Research output: Contribution to journal › Article › peer-review

Abstract

Butyl nitrite is present in consumer products subject to abuse by inhalation. When inhaled, intense peripheral vasodilation and tachycardia ensue, described by users as a ‘rush’. When ingested, toxic sequelae include methemogloginemia and hypokinetic anoxia. The median lethal oral dose to rats of this compound is, with 95% confidence, 83 ± 3.5 mg kg⁻¹.

Original language	English (US)
Pages (from-to)	30-31
Number of pages	2
Journal	Journal of Applied Toxicology
Volume	1
Issue number	1
DOIs	https://doi.org/10.1002/jat.2550010108
State	Published - Feb 1981
Externally published	Yes

Keywords

LD
butyl nitrite
inhalant abuse
oral toxicity
rat
room odorizer

ASJC Scopus subject areas

Toxicology

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10.1002/jat.2550010108

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title = "Acute oral toxicity of butyl nitrite",

abstract = "Butyl nitrite is present in consumer products subject to abuse by inhalation. When inhaled, intense peripheral vasodilation and tachycardia ensue, described by users as a {\textquoteleft}rush{\textquoteright}. When ingested, toxic sequelae include methemogloginemia and hypokinetic anoxia. The median lethal oral dose to rats of this compound is, with 95% confidence, 83 ± 3.5 mg kg−1.",

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author = "Wood, {Ronald W.} and Christopher Cox",

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AB - Butyl nitrite is present in consumer products subject to abuse by inhalation. When inhaled, intense peripheral vasodilation and tachycardia ensue, described by users as a ‘rush’. When ingested, toxic sequelae include methemogloginemia and hypokinetic anoxia. The median lethal oral dose to rats of this compound is, with 95% confidence, 83 ± 3.5 mg kg−1.

KW - LD

KW - butyl nitrite

KW - inhalant abuse

KW - oral toxicity

KW - rat

KW - room odorizer

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Acute oral toxicity of butyl nitrite

Abstract

Keywords

ASJC Scopus subject areas

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