Acute oral toxicity of butyl nitrite

R. W. Wood, Christopher Cox

Research output: Contribution to journalArticle

Abstract

Butyl nitrite is present in consumer products subject to abuse by inhalation. When inhaled, intense peripheral vasodilation and tachycardia ensue, described by users as a 'rush'. When ingested, toxic sequelae include methemoglobinemia and hypokinetic anoxia. The median lethal oral dose to rats of this compound is, with 95% confidence, 83 ± 3.5 mg kg-1.

Original languageEnglish (US)
Pages (from-to)30-31
Number of pages2
JournalJournal of Applied Toxicology
Volume1
Issue number1
StatePublished - 1981
Externally publishedYes

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Methemoglobinemia
Consumer products
Poisons
Tachycardia
Vasodilation
Inhalation
Toxicity
Rats
n-butyl nitrite
Hypoxia

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Toxicology

Cite this

Acute oral toxicity of butyl nitrite. / Wood, R. W.; Cox, Christopher.

In: Journal of Applied Toxicology, Vol. 1, No. 1, 1981, p. 30-31.

Research output: Contribution to journalArticle

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