Acute oral toxicity of butyl nitrite

Ronald W. Wood, Christopher Cox

Research output: Contribution to journalArticlepeer-review


Butyl nitrite is present in consumer products subject to abuse by inhalation. When inhaled, intense peripheral vasodilation and tachycardia ensue, described by users as a ‘rush’. When ingested, toxic sequelae include methemogloginemia and hypokinetic anoxia. The median lethal oral dose to rats of this compound is, with 95% confidence, 83 ± 3.5 mg kg−1.

Original languageEnglish (US)
Pages (from-to)30-31
Number of pages2
JournalJournal of Applied Toxicology
Issue number1
StatePublished - Feb 1981
Externally publishedYes


  • LD
  • butyl nitrite
  • inhalant abuse
  • oral toxicity
  • rat
  • room odorizer

ASJC Scopus subject areas

  • Toxicology


Dive into the research topics of 'Acute oral toxicity of butyl nitrite'. Together they form a unique fingerprint.

Cite this