TY - JOUR
T1 - Acute myocardial infarction
T2 - Safety of cardiac MR imaging after percutaneous revascularization with stents
AU - Patel, Manesh R.
AU - Albert, Timothy S.E.
AU - Kandzari, David E.
AU - Honeycutt, Emily F.
AU - Shaw, Linda K.
AU - Sketch, Michael H.
AU - Elliott, Michael D.
AU - Judd, Robert M.
AU - Kim, Raymond J.
PY - 2006/9
Y1 - 2006/9
N2 - Purpose: To retrospectively determine the safety of cardiac magnetic resonance (MR) imaging performed early (<14 days) after coronary stent implantation in patients with acute myocardial infarction (AMI). Materials and Methods: This HIPPA-compliant study was approved by the institutional review board; the informed consent requirement was waived. Consecutive patients with AMI who underwent cardiac MR imaging (study group) shortly after stent implantation (median, 3 days) were compared with control subjects who did not undergo MR imaging and were matched for clinical factors and angiographic extent of coronary disease. A 1.5-T MR imager was used to evaluate cine function, perfusion, and viability. Rates of death, non-fatal myocardial infarction, or revascularization 30 days and 6 months after stent implantation were compared with χ2 analysis. Results: The study group consisted of 66 patients (median age, 56 years; 17 women.) with 97 stents, 38 (39%) of which were drug eluting. The control group included 124 patients (median age, 58 years; 23% women) with 197 stents, 21 (10.7%) of which were drug eluting. There was no significant (P = .13) difference in the combined end point of death, nonfatal myocardial infarction, or revascularization between the study (2.0% [95% confidence interval: 0.0%, 4.5%]) and control (6.5% [95%. confidence interval: 1.6%, 11.3%]) groups at 30-day follow-up. The event-free survival rate at 6-month follow-up was 91% in the study group and 83.7% in the control group (P = .18). Considering the end points separately, there was no difference in the event rate at 30-day or 6-month follow-up between groups. No adverse cardiovascular events occurred in patients with drug-eluting stents who underwent MR imaging. Conclusion: Cardiac MR imaging performed shortly after AMI and percutaneous revascularization with bare metal or drug-eluting stents appears safe. The risk of adverse cardiovascular events is low and similar to that in patients who do not undergo MR imaging.
AB - Purpose: To retrospectively determine the safety of cardiac magnetic resonance (MR) imaging performed early (<14 days) after coronary stent implantation in patients with acute myocardial infarction (AMI). Materials and Methods: This HIPPA-compliant study was approved by the institutional review board; the informed consent requirement was waived. Consecutive patients with AMI who underwent cardiac MR imaging (study group) shortly after stent implantation (median, 3 days) were compared with control subjects who did not undergo MR imaging and were matched for clinical factors and angiographic extent of coronary disease. A 1.5-T MR imager was used to evaluate cine function, perfusion, and viability. Rates of death, non-fatal myocardial infarction, or revascularization 30 days and 6 months after stent implantation were compared with χ2 analysis. Results: The study group consisted of 66 patients (median age, 56 years; 17 women.) with 97 stents, 38 (39%) of which were drug eluting. The control group included 124 patients (median age, 58 years; 23% women) with 197 stents, 21 (10.7%) of which were drug eluting. There was no significant (P = .13) difference in the combined end point of death, nonfatal myocardial infarction, or revascularization between the study (2.0% [95% confidence interval: 0.0%, 4.5%]) and control (6.5% [95%. confidence interval: 1.6%, 11.3%]) groups at 30-day follow-up. The event-free survival rate at 6-month follow-up was 91% in the study group and 83.7% in the control group (P = .18). Considering the end points separately, there was no difference in the event rate at 30-day or 6-month follow-up between groups. No adverse cardiovascular events occurred in patients with drug-eluting stents who underwent MR imaging. Conclusion: Cardiac MR imaging performed shortly after AMI and percutaneous revascularization with bare metal or drug-eluting stents appears safe. The risk of adverse cardiovascular events is low and similar to that in patients who do not undergo MR imaging.
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U2 - 10.1148/radiol.2403050740
DO - 10.1148/radiol.2403050740
M3 - Article
C2 - 16926324
AN - SCOPUS:33747603475
SN - 0033-8419
VL - 240
SP - 674
EP - 680
JO - RADIOLOGY
JF - RADIOLOGY
IS - 3
ER -