TY - JOUR
T1 - Acute myeloid leukaemia arising from a patient with untreated essential thrombocythaemia
AU - Bolaños-Meade, Javier
AU - López-Arvizu, Carmen
AU - Cobos, Everardo
PY - 2002/6
Y1 - 2002/6
N2 - Acute myeloid leukaemia (AML) is an uncommon complication of patients with essential thrombocythaemia (ET). We report a patient with ET which progressed into AML and who had only received a few days of therapy with hydroxyurea (HU) when diagnosed with ET. This is extremely rare, as in large series no patients who were left untreated for their ET developed this complication. This case supports the theory that AML transformation can be part of the natural history of ET in some cases.
AB - Acute myeloid leukaemia (AML) is an uncommon complication of patients with essential thrombocythaemia (ET). We report a patient with ET which progressed into AML and who had only received a few days of therapy with hydroxyurea (HU) when diagnosed with ET. This is extremely rare, as in large series no patients who were left untreated for their ET developed this complication. This case supports the theory that AML transformation can be part of the natural history of ET in some cases.
KW - Acute myelogenous leukaemia
KW - Essential thrombocythaemia
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U2 - 10.1034/j.1600-0609.2002.02730.x
DO - 10.1034/j.1600-0609.2002.02730.x
M3 - Article
C2 - 12225400
AN - SCOPUS:0036620685
SN - 0902-4441
VL - 68
SP - 397
EP - 399
JO - European Journal of Haematology
JF - European Journal of Haematology
IS - 6
ER -