Acute HIV illness following blood transfusion in three African children

R. Colebunders, A. E. Greenberg, H. Francis, N. Kabote, L. Izaley, P. Nguyen-Dinh, Thomas C Quinn, G. Van Der Groen, J. W. Curran, P. Piot

Research output: Contribution to journalArticle

Abstract

Three children are described in whom pre-transfusion samples were HIV-seronegative and post-transfusional samples, obtained within 1 week after transfusion, were HIV-seropositive. Two of them developed a transient fever within 1 week of receiving the blood transfusion, and a transient generalized skin eruption which lasted for about 2 weeks. All three developed persistent generalized lymphadenopathy. One child developed a lumbar herpes zoster 7 months after transfusion. IgM Western blots demonstrated the presence of antibodies to protein bands p17, p24 and p55 in all three children. These three case reports suggest that children who receive seropositive blood transfusions are at high risk for developing acute manifestations of HIV infection.

Original languageEnglish (US)
Pages (from-to)125-127
Number of pages3
JournalAIDS
Volume2
Issue number2
StatePublished - 1988
Externally publishedYes

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Blood Transfusion
HIV
Herpes Zoster
HIV Infections
Immunoglobulin M
Fever
Western Blotting
Skin
Antibodies
Proteins

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Colebunders, R., Greenberg, A. E., Francis, H., Kabote, N., Izaley, L., Nguyen-Dinh, P., ... Piot, P. (1988). Acute HIV illness following blood transfusion in three African children. AIDS, 2(2), 125-127.

Acute HIV illness following blood transfusion in three African children. / Colebunders, R.; Greenberg, A. E.; Francis, H.; Kabote, N.; Izaley, L.; Nguyen-Dinh, P.; Quinn, Thomas C; Van Der Groen, G.; Curran, J. W.; Piot, P.

In: AIDS, Vol. 2, No. 2, 1988, p. 125-127.

Research output: Contribution to journalArticle

Colebunders, R, Greenberg, AE, Francis, H, Kabote, N, Izaley, L, Nguyen-Dinh, P, Quinn, TC, Van Der Groen, G, Curran, JW & Piot, P 1988, 'Acute HIV illness following blood transfusion in three African children', AIDS, vol. 2, no. 2, pp. 125-127.
Colebunders R, Greenberg AE, Francis H, Kabote N, Izaley L, Nguyen-Dinh P et al. Acute HIV illness following blood transfusion in three African children. AIDS. 1988;2(2):125-127.
Colebunders, R. ; Greenberg, A. E. ; Francis, H. ; Kabote, N. ; Izaley, L. ; Nguyen-Dinh, P. ; Quinn, Thomas C ; Van Der Groen, G. ; Curran, J. W. ; Piot, P. / Acute HIV illness following blood transfusion in three African children. In: AIDS. 1988 ; Vol. 2, No. 2. pp. 125-127.
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