Acute Disseminated Encephalomyelitis: Clinical and Pathogenesis Features

Farshid Noorbakhsh, Richard T. Johnson, Derek Emery, Christopher Power

Research output: Contribution to journalReview articlepeer-review

Abstract

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADEM reveals involvement of white matter, with infiltration of monocytoid cells and perivenous demyelination.

Original languageEnglish (US)
Pages (from-to)759-780
Number of pages22
JournalNeurologic clinics
Volume26
Issue number3
DOIs
StatePublished - Aug 2008

ASJC Scopus subject areas

  • Clinical Neurology

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