Acute cerebrospinal fluid pressure changes: Dynamics and effects

M. J. Holliday, D. M. Long, H. Brem, N. Bhatti, D. Backous

Research output: Contribution to journalArticlepeer-review


Sudden changes in spinal fluid pressures may occur spontaneously, intraoperalively, postoperatively and secondary 10 trauma, neoplasm and inflammatory processes. We have experienced such situations clinically, particularly in dealing with skull base pathology. Retrospective analysis of some of these clinical situations are presented along with literature review and suggestions for prevention and rapid identification and correction of the existing etiologies. Special emphasis is made to relate to conditions that are often presented to the non-neurosurgical specialties and how to recognize impending dangers. Included are situations of both high and of low pressures and their physiologic implications in different settings. Treatment considers differing settings including inpatient and outpatient, operating room, ward and intensive care units.

Original languageEnglish (US)
Number of pages1
JournalSkull Base Surgery
Issue numberSUPPL. 1
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Clinical Neurology


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