Acute and long-term results of slow pathway ablation in patients with atrioventricular nodal reentrant tachycardia - An analysis of the predictive factors for arrhythmia recurrence

Heidi Luise Estner, Gjin Ndrepepa, Jun Dong, Isabel Deisenhofer, Juergen Schreieck, Michael Schneider, Andreas Plewan, Martin Karch, Sonja Weyerbrock, Diana Wade, Bernhard Zrenner, Claus Schmitt

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

Background: Predictors of atrioventricular nodal reentrant tachycardia (AVNRT) recurrence after radiofrequency ablation including the importance of residual slow pathway conduction are not known. The aim of this study was toreport the acute and long-term results of slow pathway ablation in a large series of consecutive patients with AVNRT and to analyze the potential predictors of arrhythmia recurrence with a particular emphasis on the residual slow pathway conduction after ablation. Methods: The study included 506 consecutive patients with AVNRT (mean age 52.6 ± 16 years, 315 women) who underwent slow pathway ablation using a combined electrophysiological and anatomical approach. The end point of ablation procedure was noninducibility of the arrhythmia. The primary end point of the study was the recurrence of AVNRT. Results: Acute success was achieved in 500 patients (98.8%). After ablation, 471 patients (93%) were followed up for a mean of 903 ± 692 days. Of the 465 patients with successful ablation, 24 patients (5.2%) developed AVNRT recurrences during the follow-up. No significant differences in the cumulative rates of AVNRT recurrence were observed in groups with or without electrophysiological evidence of residual slow pathway conduction (P = 0.25, log-rank test). Multivariate analysis identified only age as an independent predictor of AVNRT recurrence (hazard ratio 0.96, 95% confidence interval 0.94-0.99, P = 0.004) with younger patients being at an increased risk for arrhythmia recurrence. Conclusions: Our study demonstrated that only younger age, but not other clinical or electrophysiological parameters including residual slow pathway conduction predicted an increased risk for AVNRT recurrence after slow pathway radiofrequency ablation.

Original languageEnglish (US)
Pages (from-to)102-110
Number of pages9
JournalPACE - Pacing and Clinical Electrophysiology
Volume28
Issue number2
DOIs
StatePublished - Feb 2005
Externally publishedYes

Keywords

  • Ablation
  • Atrioventricular nodal reentrant tachycardia
  • Recurrence
  • Slow pathway

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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