Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal.

Sahar Kohanim; Sotiria Palioura; Hajirah N. Saeed; Esen K. Akpek; Guillermo Amescua; Sayan Basu; Preston H. Blomquist; Charles S. Bouchard; John K. Dart; Xiaowu Gai; José A.P. Gomes; Darren G. Gregory; Geetha Iyer; Deborah S. Jacobs; Anthony J. Johnson; Shigeru Kinoshita; Iason S. Mantagos; Jodhbir S. Mehta; Victor L. Perez; Stephen C. Pflugfelder; Virender S. Sangwan; Kimberly C. Sippel; Chie Sotozono; Bhaskar Srinivasan; Donald T.H. Tan; Radhika Tandon; Scheffer C.G. Tseng; Mayumi Ueta; James Chodosh

doi:10.1016/j.jtos.2016.02.001

Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal.

Sahar Kohanim, Sotiria Palioura, Hajirah N. Saeed, Esen K. Akpek, Guillermo Amescua, Sayan Basu, Preston H. Blomquist, Charles S. Bouchard, John K. Dart, Xiaowu Gai, José A.P. Gomes, Darren G. Gregory, Geetha Iyer, Deborah S. Jacobs, Anthony J. Johnson, Shigeru Kinoshita, Iason S. Mantagos, Jodhbir S. Mehta, Victor L. Perez, Stephen C. PflugfelderVirender S. Sangwan, Kimberly C. Sippel, Chie Sotozono, Bhaskar Srinivasan, Donald T.H. Tan, Radhika Tandon, Scheffer C.G. Tseng, Mayumi Ueta, James Chodosh

School of Medicine

Research output: Contribution to journal › Review article › peer-review

87 Scopus citations

Abstract

Our purpose is to comprehensively review the state of the art with regard to Stevens- Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with particular attention to improving the management of associated ocular surface complications. SJS and TEN are two ends of a spectrum of immune-mediated disease, characterized in the acute phase by a febrile illness followed by skin and mucous membrane necrosis and detachment. Part I of this review focused on the systemic aspects of SJS/TEN and was published in the January 2016 issue of this journal. The purpose of Part II is to summarize the ocular manifestations and their management through all phases of SJS/TEN, from acute to chronic. We hope this effort will assist ophthalmologists in their management of SJS/TEN, so that patients with this complex and debilitating disease receive the best possible care and experience the most optimal outcomes in their vision and quality of life.

Original language	English (US)
Pages (from-to)	168-188
Number of pages	21
Journal	Ocular Surface
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/j.jtos.2016.02.001
State	Published - Apr 1 2016

Keywords

Stevens-Johnson Syndrome
amniotic membrane transplantation
apoptosis
drug-induced disease
immune-mediated disease
keratinocyte death
keratoprosthesis
ocular surface reconstruction
toxic epidermal necrolysis

ASJC Scopus subject areas

Ophthalmology

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Kohanim, S., Palioura, S., Saeed, H. N., Akpek, E. K., Amescua, G., Basu, S., Blomquist, P. H., Bouchard, C. S., Dart, J. K., Gai, X., Gomes, J. A. P., Gregory, D. G., Iyer, G., Jacobs, D. S., Johnson, A. J., Kinoshita, S., Mantagos, I. S., Mehta, J. S., Perez, V. L., ... Chodosh, J. (2016). Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal. Ocular Surface, 14(2), 168-188. https://doi.org/10.1016/j.jtos.2016.02.001

Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal. / Kohanim, Sahar; Palioura, Sotiria; Saeed, Hajirah N. et al.
In: Ocular Surface, Vol. 14, No. 2, 01.04.2016, p. 168-188.

Research output: Contribution to journal › Review article › peer-review

Kohanim, S, Palioura, S, Saeed, HN, Akpek, EK, Amescua, G, Basu, S, Blomquist, PH, Bouchard, CS, Dart, JK, Gai, X, Gomes, JAP, Gregory, DG, Iyer, G, Jacobs, DS, Johnson, AJ, Kinoshita, S, Mantagos, IS, Mehta, JS, Perez, VL, Pflugfelder, SC, Sangwan, VS, Sippel, KC, Sotozono, C, Srinivasan, B, Tan, DTH, Tandon, R, Tseng, SCG, Ueta, M & Chodosh, J 2016, 'Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal.', Ocular Surface, vol. 14, no. 2, pp. 168-188. https://doi.org/10.1016/j.jtos.2016.02.001

Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S et al. Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal. Ocular Surface. 2016 Apr 1;14(2):168-188. doi: 10.1016/j.jtos.2016.02.001

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abstract = "Our purpose is to comprehensively review the state of the art with regard to Stevens- Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), with particular attention to improving the management of associated ocular surface complications. SJS and TEN are two ends of a spectrum of immune-mediated disease, characterized in the acute phase by a febrile illness followed by skin and mucous membrane necrosis and detachment. Part I of this review focused on the systemic aspects of SJS/TEN and was published in the January 2016 issue of this journal. The purpose of Part II is to summarize the ocular manifestations and their management through all phases of SJS/TEN, from acute to chronic. We hope this effort will assist ophthalmologists in their management of SJS/TEN, so that patients with this complex and debilitating disease receive the best possible care and experience the most optimal outcomes in their vision and quality of life.",

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AU - Dart, John K.

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Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Part i (Systemic Disease) was published in the January 2016 issue of this journal.

Abstract

Keywords

ASJC Scopus subject areas

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