Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines

Engineering & Materials Science

• Dendrimers 100%
• Cells 54%
• Amines 33%
• Carboxylic acids 21%
• Amides 21%
• Drug delivery 18%
• Oxidoreductases 10%
• Chemotherapy 10%
• Cytotoxicity 10%
• Functional groups 9%
• Nanostructures 8%
• Enzymes 8%

Medicine & Life Sciences

• Dendrimers 76%
• Methotrexate 54%
• Cell Line 33%
• Amines 18%
• Carboxylic Acids 11%
• Amides 10%
• Pharmaceutical Preparations 7%
• Dicyclohexylcarbodiimide 6%
• Nanostructures 5%
• Cricetulus 4%
• Adenosine 4%
• Drug Liberation 4%
• Thymidine 4%
• Oxidoreductases 3%
• Inhibitory Concentration 50 3%
• Ovary 3%
• Therapeutic Uses 3%
• Leukemia 3%
• Drug Therapy 2%
• Enzymes 2%

Chemical Compounds

• Methotrexate 46%
• Dendrimer 27%
• Amine 8%
• Drug 7%
• Residence Time 4%
• Adenosine 4%
• Coupling Reaction 4%
• Carboxylic Acid 3%
• Surface 2%
• Nanomaterial 2%
• Amount 1%