Activities of Nigerian chewing stick extracts against Bacteroides gingivalis and Bacteroides melaninogenicus

V. O. Rotimi, B. E. Laughon, J. G. Bartlett, H. A. Mosadomi

Research output: Contribution to journalArticlepeer-review

75 Scopus citations

Abstract

The in vitro activities of extracts of Nigerian chewing sticks against Bacteroides gingivalis and B. melaninogenicus are presented. The greatest inhibitory action was produced by Serindeia werneckei, whereas Fagara zanthoxyloides produced no appreciable inhibitory effect. A generally good correlation was found between the killing curves and MICs. Only extracts of Anogeissus leiocarpus showed acute toxicity in mice.

Original languageEnglish (US)
Pages (from-to)598-600
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume32
Issue number4
DOIs
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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