Active two-channel 0.035″ guidewire for interventional cardiovascular MRI

Ozgur Kocaturk, Ann H. Kim, Christina E. Saikus, Michael A. Guttman, Anthony Z. Faranesh, Cengizhan Ozturk, Robert J. Lederman

Research output: Contribution to journalArticle

Abstract

Purpose: To develop an "active" (receiver-coil) clinical-grade guidewire with enhanced visibility for magnetic resonance imaging (MRI) and favorable mechanical characteristics for interventional MRI procedures that require conspicuous intravascular instruments distinguishable from surrounding tissues. Materials and Methods: We designed a 0.035-inch guidewire combining two antenna designs on separate channels. A loop antenna visualizes the tip and a dipole antenna visualizes the whole shaft. We compared mechanical characteristics of this guidewire with x-ray alternatives and tested MRI performance at 1.5T in vitro and in vivo in swine. Results: Images reflected tip position within 0.97 ± 0.42 mm and afforded whole-shaft visibility under expected conditions without sacrificing device size or handling. We report tip stiffness, torquability, and pushability comparable to commercial interventional guidewires. Conclusion: Our clinical-grade 0.035-inch active guidewire is conspicuous under MRI and has mechanical performance comparable to x-ray interventional guidewires. This may enable a range of interventional procedures using real-time MRI.

Original languageEnglish (US)
Pages (from-to)461-465
Number of pages5
JournalJournal of Magnetic Resonance Imaging
Volume30
Issue number2
DOIs
StatePublished - Aug 1 2009

Keywords

  • Active instrument
  • Catheterization methods
  • Equipment design
  • Interventional magnetic resonance imaging methods

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Kocaturk, O., Kim, A. H., Saikus, C. E., Guttman, M. A., Faranesh, A. Z., Ozturk, C., & Lederman, R. J. (2009). Active two-channel 0.035″ guidewire for interventional cardiovascular MRI. Journal of Magnetic Resonance Imaging, 30(2), 461-465. https://doi.org/10.1002/jmri.21844