Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil

Denise Rossato Silva, Alice Manica Müller, Karina Da Silva Tomasini, Paulo De Tarso Roth Dalcin, Jonathan E Golub, Marcus Barreto Conde

Research output: Contribution to journalArticle

Abstract

Setting: Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. Objective: To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis. Methods: Cross sectional study. All patients ≥18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acidfast bacilli smear and culture. Results: Among 31,267 admissions, 6,273 (20.1%) reported respiratory symptoms; 197 reported cough ≥2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: Age (OR 0.94, 95% CI: 0.92-0.97; p

Original languageEnglish (US)
Article numbere107576
JournalPLoS One
Volume9
Issue number9
DOIs
StatePublished - Sep 1 2014

Fingerprint

Emergency rooms
Pulmonary Tuberculosis
tuberculosis
Brazil
Hospital Emergency Service
Tuberculosis
Public Hospitals
Viruses
Cough
signs and symptoms (animals and humans)
HIV
cough
lungs
Bacilli
Virus Diseases
Sputum
Bacillus
Thorax
Multivariate Analysis
Cross-Sectional Studies

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Silva, D. R., Müller, A. M., Da Silva Tomasini, K., De Tarso Roth Dalcin, P., Golub, J. E., & Conde, M. B. (2014). Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. PLoS One, 9(9), [e107576]. https://doi.org/10.1371/journal.pone.0107576

Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. / Silva, Denise Rossato; Müller, Alice Manica; Da Silva Tomasini, Karina; De Tarso Roth Dalcin, Paulo; Golub, Jonathan E; Conde, Marcus Barreto.

In: PLoS One, Vol. 9, No. 9, e107576, 01.09.2014.

Research output: Contribution to journalArticle

Silva, DR, Müller, AM, Da Silva Tomasini, K, De Tarso Roth Dalcin, P, Golub, JE & Conde, MB 2014, 'Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil', PLoS One, vol. 9, no. 9, e107576. https://doi.org/10.1371/journal.pone.0107576
Silva, Denise Rossato ; Müller, Alice Manica ; Da Silva Tomasini, Karina ; De Tarso Roth Dalcin, Paulo ; Golub, Jonathan E ; Conde, Marcus Barreto. / Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil. In: PLoS One. 2014 ; Vol. 9, No. 9.
@article{d4f404afb4034606af880274f322c442,
title = "Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil",
abstract = "Setting: Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. Objective: To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis. Methods: Cross sectional study. All patients ≥18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acidfast bacilli smear and culture. Results: Among 31,267 admissions, 6,273 (20.1{\%}) reported respiratory symptoms; 197 reported cough ≥2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: Age (OR 0.94, 95{\%} CI: 0.92-0.97; p",
author = "Silva, {Denise Rossato} and M{\"u}ller, {Alice Manica} and {Da Silva Tomasini}, Karina and {De Tarso Roth Dalcin}, Paulo and Golub, {Jonathan E} and Conde, {Marcus Barreto}",
year = "2014",
month = "9",
day = "1",
doi = "10.1371/journal.pone.0107576",
language = "English (US)",
volume = "9",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "9",

}

TY - JOUR

T1 - Active case finding of tuberculosis (TB) in an emergency room in a region with high prevalence of TB in Brazil

AU - Silva, Denise Rossato

AU - Müller, Alice Manica

AU - Da Silva Tomasini, Karina

AU - De Tarso Roth Dalcin, Paulo

AU - Golub, Jonathan E

AU - Conde, Marcus Barreto

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Setting: Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. Objective: To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis. Methods: Cross sectional study. All patients ≥18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acidfast bacilli smear and culture. Results: Among 31,267 admissions, 6,273 (20.1%) reported respiratory symptoms; 197 reported cough ≥2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: Age (OR 0.94, 95% CI: 0.92-0.97; p

AB - Setting: Public hospital emergency room (ER) in Porto Alegre, Brazil, a setting with high prevalence of tuberculosis (TB) and human immunodeficiency virus (HIV) infection. Objective: To determine the prevalence of PTB, using a symptom based active case finding (ACF) strategy in the ER of a public hospital in an area with high prevalence of TB and HIV, as well as variables associated with pulmonary TB diagnosis. Methods: Cross sectional study. All patients ≥18 years seeking care at the ER were screened for respiratory symptoms and those with cough ≥2 weeks were invited to provide a chest radiograph and two unsupervised samples of sputum for acidfast bacilli smear and culture. Results: Among 31,267 admissions, 6,273 (20.1%) reported respiratory symptoms; 197 reported cough ≥2 weeks, of which pulmonary TB was diagnosed in 30. In multivariate analysis, the variables associated with a pulmonary tuberculosis diagnosis were: Age (OR 0.94, 95% CI: 0.92-0.97; p

UR - http://www.scopus.com/inward/record.url?scp=84944929771&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944929771&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0107576

DO - 10.1371/journal.pone.0107576

M3 - Article

C2 - 25211158

AN - SCOPUS:84944929771

VL - 9

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 9

M1 - e107576

ER -