Activation of the cGMP/protein kinase G pathway by nitric oxide can decrease TRPV1 activity in cultured rat dorsal root ganglion neurons

Medicine & Life Sciences

• Cyclic GMP-Dependent Protein Kinases 100%
• Spinal Ganglia 81%
• Nitroprusside 67%
• Nitric Oxide 61%
• Neurons 46%
• S-nitro-N-acetylpenicillamine 32%
• 8-bromoguanosine 27%
• 8-((4-chlorophenyl)thio)cyclic-3',5'-GMP 27%
• 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole 24%
• KT 5823 23%
• Soluble Guanylyl Cyclase 19%
• Guanylate Cyclase 18%
• Guanosine 18%
• Nitric Oxide Donors 18%
• Capsaicin 17%
• Sensory Receptor Cells 16%
• Protein Kinase Inhibitors 15%
• Proteins 11%
• Down-Regulation 10%
• Membranes 8%