Acrylamide polymerization: New method for determining the oxygen content in blood

Judah Folkman, Howard Conn, Richard Harmel

Research output: Contribution to journalArticlepeer-review

Abstract

A new principle for determining the oxygen content of 0.1-milliliter blood samples has been developed, based on measurement of the delay in gelation during copolymerization of acrylamide and bisacrylamide initiated by free radicals. The logarithm of this time interval is linearly proportional to the oxygen content of the blood sample over the range 0 to 22 milliliters of oxygen per 100 milliliters of whole blood. Physiological variations of pH and pCO2 do not affect the sensitivity of the assay.

Original languageEnglish (US)
Pages (from-to)170-172
Number of pages3
JournalScience
Volume178
Issue number4057
DOIs
StatePublished - Jan 1 1972

ASJC Scopus subject areas

  • General

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