Abstract
Acquired immunity to malaria was investigated in mice which had recovered from a primary infection with P. b. yoelii. It was found that antibody synthesis and protection persisted at least 17 months, although both decreased somewhat during this interval. Strong cross-protection was exhibited against a virulent isolate of the parent strain but not against the type species, P. b. berghei. It was not possible to detect persisting antigen or persisting infectious organisms in immune mice; both blood-induced and sporozoite- induced infections were followed from this standpoint.
Original language | English (US) |
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Pages (from-to) | 586-590 |
Number of pages | 5 |
Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene |
Volume | 65 |
Issue number | 5 |
DOIs | |
State | Published - 1971 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Public Health, Environmental and Occupational Health
- Infectious Diseases