Lupus erythematosus profundus (LEP) is an uncommon subtype of lupus erythematosus. A 76-year old man presented with inflammation of the eyelids and underlying orbital soft tissue. A biopsy disclosed inflammation and atrophy of the orbital fat consistent with LEP. Systemic corticosteroid treatment produced resolution of the inflammation. but as the edema subsided, enophthalmos became apparent. LEP should be considered in patients with a characteristic rash and orbital inflammation and may cause acquired enophthalmos.
ASJC Scopus subject areas
- Clinical Neurology