Acid sphingomyelinase deficiency increases susceptibility to fatal alphavirus encephalomyelitis

Medicine & Life Sciences

• Type A Niemann-Pick Disease 100%
• Sindbis Virus 85%
• Alphavirus 81%
• Encephalomyelitis 81%
• Acids 44%
• Sphingomyelins 33%
• Sphingomyelin Phosphodiesterase 29%
• Knockout Mice 24%
• Interleukin-6 12%
• Virus Diseases 11%
• Togaviridae 8%
• Nervous System 8%
• mouse interleukin-6 8%
• RNA 7%
• Neurons 6%
• Sphingolipids 6%
• DNA Nucleotidylexotransferase 6%
• Biotin 5%
• Interleukin-1 5%
• Brain 5%
• In Situ Hybridization 4%
• Transgenic Mice 4%
• Mammals 4%
• Hippocampus 4%
• Tumor Necrosis Factor-alpha 3%
• Immunohistochemistry 3%
• Genome 3%
• Viruses 3%
• Apoptosis 3%
• Animals 2%
• Genes 2%
• Proteins 1%

Agriculture & Biology

• Sindbis virus 86%
• Alphavirus 85%
• encephalitis 71%
• mice 34%
• acids 32%
• interleukin-6 23%
• nervous system 11%
• neurons 8%
• Togaviridae 8%
• infection 8%
• brain 7%
• RNA 7%
• sphingolipids 6%
• interleukin-1 6%
• hippocampus 6%
• biotin 5%
• tumor necrosis factor-alpha 5%
• immunohistochemistry 5%
• in situ hybridization 4%
• apoptosis 4%
• pathogenesis 4%
• cortex 4%
• immatures 4%
• death 4%
• genetically modified organisms 4%
• mammals 3%
• viruses 3%
• genome 2%
• animals 2%
• genes 1%
• proteins 1%
• cells 1%