Achieving 1% NMR polarization in water in less than 1 min using SABRE

Haifeng Zeng, Jiadi Xu, Michael T. McMahon, Joost A.B. Lohman, Peter C.M. Van Zijl

Research output: Contribution to journalArticlepeer-review

Abstract

The development of biocompatible hyperpolarized media is a crucial step towards application of hyperpolarization in vivo. This article describes the achievement of 1% hyperpolarization of 3-amino-1,2,4-triazine protons in water using the parahydrogen induced polarization technique based on signal amplification by reversible exchange (SABRE). Polarization was achieved in less than 1 min.

Original languageEnglish (US)
Pages (from-to)119-121
Number of pages3
JournalJournal of Magnetic Resonance
Volume246
DOIs
StatePublished - Sep 2014

Keywords

  • Hyperpolarization
  • Parahydrogen
  • SABRE

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics

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