Acetylation of unsymmetrical diols in the presence of Al2O3

Gary W. Breton, Melissa Kurtz, Sharyn L. Kurtz

Research output: Contribution to journalArticle

Abstract

The effect of the presence of chromatographic grade Al2O3 on the acetylation of a series of unsymmetrical 1,5-diols was investigated. For diols containing both a primary and a secondary hydroxyl group, it was observed that higher yields of the more hindered secondary acetates were formed in the presence of Al2O3 than the corresponding reactions in solution.

Original languageEnglish (US)
Pages (from-to)3825-3828
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number22
DOIs
StatePublished - Jun 2 1997
Externally publishedYes

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Acetylation
Hydroxyl Radical
Acetates

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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Acetylation of unsymmetrical diols in the presence of Al2O3 . / Breton, Gary W.; Kurtz, Melissa; Kurtz, Sharyn L.

In: Tetrahedron Letters, Vol. 38, No. 22, 02.06.1997, p. 3825-3828.

Research output: Contribution to journalArticle

Breton, Gary W. ; Kurtz, Melissa ; Kurtz, Sharyn L. / Acetylation of unsymmetrical diols in the presence of Al2O3 In: Tetrahedron Letters. 1997 ; Vol. 38, No. 22. pp. 3825-3828.
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