Acellular dermal graft (AlloDerm) for upper eyelid reconstruction after cancer removal

Brent Hayek, Elham Hatef, Michael Nguyen, Viet Ho, Adam Hsu, Bita Esmaeli

Research output: Contribution to journalArticle

Abstract

Purpose: To report the use of AlloDerm for reconstruction of large upper eyelid defects in cancer patients. Methods: The clinical records of all patients who had AlloDerm as part of their upper eyelid reconstruction between July 2005 and July 2006 at a single institution were reviewed. Functional and cosmetic outcomes and postoperative complications were assessed. Results: Two patients had recurrent sebaceous gland carcinoma, 2 had melanoma, and 1 had squamous cell carcinoma. The upper eyelid defect involved the full thickness and entire width of the upper eyelid in 4 patients and full thickness and two thirds of the upper eye eyelid in 1 patient. The reconstructive procedure included a modified Cutler-Beard procedure using AlloDerm as the posterior lamellar sandwich graft in all 5 patients. One patient had early postoperative adjuvant radiation therapy to the upper eyelid. Three patients had excellent functional and cosmetic outcome; 2 patients had satisfactory outcomes. Two patients had residual exposure keratopathy. Allergic reaction to AlloDerm, infectious transmission, and immunologic rejection were not encountered at the time of this report (mean follow-up time = 13 months). Conclusions: AlloDerm can be used as an alternative sandwich graft material to replace the tarsus for reconstruction of large upper eyelid defects using a modified Cutler-Beard procedure.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalOphthalmic Plastic and Reconstructive Surgery
Volume25
Issue number6
DOIs
StatePublished - Nov 2009
Externally publishedYes

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Eyelids
Transplants
Skin
Neoplasms
Cosmetics
Alloderm
Sebaceous Glands
Ankle
Squamous Cell Carcinoma
Melanoma
Hypersensitivity
Radiotherapy
Carcinoma

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

Cite this

Acellular dermal graft (AlloDerm) for upper eyelid reconstruction after cancer removal. / Hayek, Brent; Hatef, Elham; Nguyen, Michael; Ho, Viet; Hsu, Adam; Esmaeli, Bita.

In: Ophthalmic Plastic and Reconstructive Surgery, Vol. 25, No. 6, 11.2009, p. 426-429.

Research output: Contribution to journalArticle

Hayek, Brent ; Hatef, Elham ; Nguyen, Michael ; Ho, Viet ; Hsu, Adam ; Esmaeli, Bita. / Acellular dermal graft (AlloDerm) for upper eyelid reconstruction after cancer removal. In: Ophthalmic Plastic and Reconstructive Surgery. 2009 ; Vol. 25, No. 6. pp. 426-429.
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