Accuracy of lesion boundary tracking in navigated breast tumor excision

Emily Heffernan, Tamas Ungi, Thomas Vaughan, Padina Pezeshki, Andras Lasso, Gabrielle Gauvin, John Rudan, C. Jay Engel, Evelyn Morin, Gabor Fichtinger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

PURPOSE: An electromagnetic navigation system for tumor excision in breast conserving surgery has recently been developed. Preoperatively, a hooked needle is positioned in the tumor and the tumor boundaries are defined in the needle coordinate system. The needle is tracked electromagnetically throughout the procedure to localize the tumor. However, the needle may move and the tissue may deform, leading to errors in maintaining a correct excision boundary. It is imperative to quantify these errors so the surgeon can choose an appropriate resection margin. METHODS: A commercial breast biopsy phantom with several inclusions was used. Location and shape of a lesion before and after mechanical deformation were determined using 3D ultrasound volumes. Tumor location and shape were estimated from initial contours and tracking data. The difference in estimated and actual location and shape of the lesion after deformation was quantified using the Hausdorff distance. Data collection and analysis were done using our 3D Slicer software application and PLUS toolkit. RESULTS: The deformation of the breast resulted in 3.72 mm (STD 0.67 mm) average boundary displacement for an isoelastic lesion and 3.88 mm (STD 0.43 mm) for a hyperelastic lesion. The difference between the actual and estimated tracked tumor boundary was 0.88 mm (STD 0.20 mm) for the isoelastic and 1.78 mm (STD 0.18 mm) for the hyperelastic lesion. CONCLUSION: The average lesion boundary tracking error was below 2mm, which is clinically acceptable. We suspect that stiffness of the phantom tissue affected the error measurements. Results will be validated in patient studies.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling
PublisherSPIE
Volume9786
ISBN (Electronic)9781510600218
DOIs
StatePublished - 2016
Externally publishedYes
EventMedical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States
Duration: Feb 28 2016Mar 1 2016

Other

OtherMedical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego
Period2/28/163/1/16

Keywords

  • Breast-conserving surgery
  • electromagnetic tracking
  • lumpectomy
  • tracking validation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Heffernan, E., Ungi, T., Vaughan, T., Pezeshki, P., Lasso, A., Gauvin, G., Rudan, J., Engel, C. J., Morin, E., & Fichtinger, G. (2016). Accuracy of lesion boundary tracking in navigated breast tumor excision. In Medical Imaging 2016: Image-Guided Procedures, Robotic Interventions, and Modeling (Vol. 9786). [97860Y] SPIE. https://doi.org/10.1117/12.2217017