Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction

Bernhard L. Gerber, Jérôme Garot, David A. Bluemke, Katherine Chih-Ching Wu, Joao Lima

Research output: Contribution to journalArticle

Abstract

Background - Contrast-enhanced (CE) MRI demonstrates a pattern of hypoenhancement early after contrast injection in acute myocardial infarction (MI) and a pattern of hyperenhancement late after contrast injection. Because the significance of these CE patterns for myocardial viability remains debated, we evaluated their diagnostic accuracy to quantitatively predict late functional improvement of regional contractility. Methods and Results - Twenty patients underwent CE and tagged MRI at 4 days and again at 7 months after acute MI. Resting circumferential shortening strain (Ecc) was analyzed in 24 segments per patient, and its improvement was correlated with the presence or absence of the CE patterns. Immediately after MI, 389 segments were considered dysfunctional because of having less than mean±2 SD Ecc of the remote region (-18±4%). At follow-up, significant improvement of Ecc occurred in 170 dysfunctional segments with normal CE (from -4±7% to -12±7%, P

Original languageEnglish (US)
Pages (from-to)1083-1089
Number of pages7
JournalCirculation
Volume106
Issue number9
DOIs
StatePublished - Aug 27 2002

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Myocardial Infarction
Magnetic Resonance Imaging
Injections

Keywords

  • Hibernation
  • Magnetic resonance imaging
  • Myocardial infarction
  • Myocardial stunning

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Accuracy of contrast-enhanced magnetic resonance imaging in predicting improvement of regional myocardial function in patients after acute myocardial infarction. / Gerber, Bernhard L.; Garot, Jérôme; Bluemke, David A.; Wu, Katherine Chih-Ching; Lima, Joao.

In: Circulation, Vol. 106, No. 9, 27.08.2002, p. 1083-1089.

Research output: Contribution to journalArticle

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AU - Garot, Jérôme

AU - Bluemke, David A.

AU - Wu, Katherine Chih-Ching

AU - Lima, Joao

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