Abstract
Purpose: To determine the accuracy of breath-hold magnetic resonance (MR) imaging for preoperative staging of patients with organ-confined (stage I) renal cell carcinoma. Materials and Methods: Preoperative MR examinations of 43 patients (50 lesions) who underwent nephrectomy were reviewed. The MR examination consisted entirely of breath-hold sequences, and images were retrospectively evaluated by 2 blinded radiologists. Reviewers independently evaluated each case for findings that could affect the radiologic staging, particularly those that distinguish between organ-confined (stage I) and non-organ-confined (>stage II) disease. Each reviewer assigned a stage, and results were correlated with findings at surgery and pathologic examination. Results: The difference between both reviewers and pathologic findings in evaluating an intact renal capsule (stage I) was statistically significant (P < 0.05) and resulted in a statistically significant difference between radiologic and pathologic staging (Wilcoxon test, P < 0.05). The κ test demonstrated moderate agreement between radiologic and pathologic staging (82% and 80% for reviewers 1 and 2, κ = 0.54 and 0.80, respectively) and substantial agreement (90%, κ = 0.80) between the 2 reviewers in assigning a radiologic stage. Conclusion: Breath-hold MR imaging has an accuracy ranging between 80% and 82% in staging patients with organ-confined renal cell carcinoma, with substantial (90%) agreement between readers.
Original language | English (US) |
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Pages (from-to) | 327-332 |
Number of pages | 6 |
Journal | Journal of computer assisted tomography |
Volume | 28 |
Issue number | 3 |
DOIs | |
State | Published - 2004 |
Keywords
- Kidney
- Magnetic resonance imaging
- Neoplasm
- Staging
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging