Accuracy analysis in MRI-guided robotic prostate biopsy

Helen Xu, Andras Lasso, Peter Guion, Axel Krieger, Aradhana Kaushal, Anurag K. Singh, Peter A. Pinto, Jonathan Coleman, Robert L. Grubb, Jean Baptiste Lattouf, Cynthia Menard, Louis L. Whitcomb, Gabor Fichtinger

Research output: Contribution to journalArticle

Abstract

Purpose: To assess retrospectively the clinical accuracy of an magnetic resonance imaging-guided robotic prostate biopsy system that has been used in the US National Cancer Institute for over 6 years. Methods: Series of 2D transverse volumetric MR image slices of the prostate both pre (high-resolution T2-weighted)- and post (low-resolution)- needle insertions were used to evaluate biopsy accuracy. A three-stage registration algorithm consisting of an initial two-step rigid registration followed by a B-spline deformable alignment was developed to capture prostate motion during biopsy. The target displacement (distance between planned and actual biopsy target), needle placement error (distance from planned biopsy target to needle trajectory), and biopsy error (distance from actual biopsy target to needle trajectory) were calculated as accuracy assessment. Results: A total of 90 biopsies from 24 patients were studied. The registrations were validated by checking prostate contour alignment using image overlay, and the results were accurate to within 2 mm. The mean target displacement, needle placement error, and clinical biopsy error were 5.2, 2.5, and 4.3 mm, respectively. Conclusion: The biopsy error reported suggests that quantitative imaging techniques for prostate registration and motion compensation may improve prostate biopsy targeting accuracy.

Original languageEnglish (US)
Pages (from-to)937-944
Number of pages8
JournalInternational journal of computer assisted radiology and surgery
Volume8
Issue number6
DOIs
StatePublished - Nov 2013

Fingerprint

Biopsy
Robotics
Magnetic resonance imaging
Prostate
Needles
Needle Biopsy
Trajectories
National Cancer Institute (U.S.)
Imaging techniques
Motion compensation
Magnetic resonance
Splines
Magnetic Resonance Imaging

Keywords

  • Accuracy validation
  • Image registration
  • MRI-guidance
  • Prostate biopsy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Health Informatics
  • Surgery

Cite this

Xu, H., Lasso, A., Guion, P., Krieger, A., Kaushal, A., Singh, A. K., ... Fichtinger, G. (2013). Accuracy analysis in MRI-guided robotic prostate biopsy. International journal of computer assisted radiology and surgery, 8(6), 937-944. https://doi.org/10.1007/s11548-013-0831-9

Accuracy analysis in MRI-guided robotic prostate biopsy. / Xu, Helen; Lasso, Andras; Guion, Peter; Krieger, Axel; Kaushal, Aradhana; Singh, Anurag K.; Pinto, Peter A.; Coleman, Jonathan; Grubb, Robert L.; Lattouf, Jean Baptiste; Menard, Cynthia; Whitcomb, Louis L.; Fichtinger, Gabor.

In: International journal of computer assisted radiology and surgery, Vol. 8, No. 6, 11.2013, p. 937-944.

Research output: Contribution to journalArticle

Xu, H, Lasso, A, Guion, P, Krieger, A, Kaushal, A, Singh, AK, Pinto, PA, Coleman, J, Grubb, RL, Lattouf, JB, Menard, C, Whitcomb, LL & Fichtinger, G 2013, 'Accuracy analysis in MRI-guided robotic prostate biopsy', International journal of computer assisted radiology and surgery, vol. 8, no. 6, pp. 937-944. https://doi.org/10.1007/s11548-013-0831-9
Xu, Helen ; Lasso, Andras ; Guion, Peter ; Krieger, Axel ; Kaushal, Aradhana ; Singh, Anurag K. ; Pinto, Peter A. ; Coleman, Jonathan ; Grubb, Robert L. ; Lattouf, Jean Baptiste ; Menard, Cynthia ; Whitcomb, Louis L. ; Fichtinger, Gabor. / Accuracy analysis in MRI-guided robotic prostate biopsy. In: International journal of computer assisted radiology and surgery. 2013 ; Vol. 8, No. 6. pp. 937-944.
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