Abstract
Resolution of inflammation is a critical process that is facilitated by specialized proresolving mediators (SPMs). In this issue, Bang et al. show that the G protein-coupled receptor GPR37 is a receptor for one such SPM, neuroprotectin D1. They also show that GPR37 activation in macrophages enhances phagocytosis, shifts cytokine release toward an antiinflammatory profile, and thereby helps to reverse inflammatory pain.
Original language | English (US) |
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Pages (from-to) | 3246-3249 |
Number of pages | 4 |
Journal | Journal of Clinical Investigation |
Volume | 128 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2018 |
ASJC Scopus subject areas
- General Medicine