Zomepirac sodium, a nonsteroidal anti- inflammatory analgesic, was compared to morphine sulfate and placebo in an abuse liability study in a postaddiction population. Morphine (15 and 30 mg), but not zomepirac (400 and 800 mg), induced pupillary constriction and characteristic morphinelike subjective effects. The 800-mg dose of zomepirac was discriminated but was not euphorigenic. This study indicates that zomepirac is not likely to be abused.
|Original language||English (US)|
|Number of pages||4|
|Journal||Clinical Pharmacology and Therapeutics|
|State||Published - Sep 1983|
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