Absence of interaction between furosemide and mitomycin C

J. Verweij, S. Kerpel-Fronius, M. Stuurman, J. de Vries, H. M. Pinedo

Research output: Contribution to journalArticlepeer-review

Abstract

The possible interaction between furosemide and mitomycin C (MMC) was studied in five patients. The pharmacokinetics of MMC were studied using an HPLC assay. Furosemide was administered prior to, or 120 min after MMC. Furosemide did not change the pharmacokinetics of MMC, nor did it change the amount of MMC excreted in the urine. There appears to be no interaction between the two drugs.

Original languageEnglish (US)
Pages (from-to)84-86
Number of pages3
JournalCancer Chemotherapy and Pharmacology
Volume19
Issue number1
DOIs
StatePublished - Feb 1987
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Oncology
  • Cancer Research

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