ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS.

Masafumi Kitakaze, M. Hori, Y. Ishida, M. Fukunami, H. Kusuoka, T. Kigiya, A. Kitabatake, M. Inoue, H. Abe, K. Tsujioka, S. Nakajima

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Augmented stroke volume (SV) accompanies an increase in ejection velocity (Ve). To determine whether Ve directly affects the LV relaxation rate irrespective of SV changes, the time constant (T) of isovolumic LV pressure (LVP) decay was studied in 8 isolated canine hearts. A water-filled balloon was inserted into LV cavity and instantaneous LV volume was controlled by servo-pump. To eliminate the effect of SV, end-systolic and end-diastolic volumes were clamped and LV was allowed to eject with 3-5 different velocities under two conditions; with mid-ejection time and with end of ejection unchanged. In any condition, T was not significantly altered by Ve changes. Thus, we conclude that LV relaxation rate is not influenced by ejection velocity. Enhanced LV relaxation rate in augmented SV may be due to the direct effect of the extent of muscle shortening.

Original languageEnglish (US)
Title of host publicationJapanese Journal of Medical Electronics and Biological Engineering
PublisherJapan Soc of Medical Electronics & Biological Engineering
Pages126-127
Number of pages2
Volume22
StatePublished - Apr 1984
Externally publishedYes

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Balloons
Muscle
Pumps
Water

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Kitakaze, M., Hori, M., Ishida, Y., Fukunami, M., Kusuoka, H., Kigiya, T., ... Nakajima, S. (1984). ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS. In Japanese Journal of Medical Electronics and Biological Engineering (Vol. 22, pp. 126-127). Japan Soc of Medical Electronics & Biological Engineering.

ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS. / Kitakaze, Masafumi; Hori, M.; Ishida, Y.; Fukunami, M.; Kusuoka, H.; Kigiya, T.; Kitabatake, A.; Inoue, M.; Abe, H.; Tsujioka, K.; Nakajima, S.

Japanese Journal of Medical Electronics and Biological Engineering. Vol. 22 Japan Soc of Medical Electronics & Biological Engineering, 1984. p. 126-127.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kitakaze, M, Hori, M, Ishida, Y, Fukunami, M, Kusuoka, H, Kigiya, T, Kitabatake, A, Inoue, M, Abe, H, Tsujioka, K & Nakajima, S 1984, ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS. in Japanese Journal of Medical Electronics and Biological Engineering. vol. 22, Japan Soc of Medical Electronics & Biological Engineering, pp. 126-127.
Kitakaze M, Hori M, Ishida Y, Fukunami M, Kusuoka H, Kigiya T et al. ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS. In Japanese Journal of Medical Electronics and Biological Engineering. Vol. 22. Japan Soc of Medical Electronics & Biological Engineering. 1984. p. 126-127
Kitakaze, Masafumi ; Hori, M. ; Ishida, Y. ; Fukunami, M. ; Kusuoka, H. ; Kigiya, T. ; Kitabatake, A. ; Inoue, M. ; Abe, H. ; Tsujioka, K. ; Nakajima, S. / ABSENCE OF DIRECT EFFECT OF EJECTION VELOCITY ON LV RELAXATION RATE IN LV VOLUME CONTROLLED ISOLATED CANINE HEARTS. Japanese Journal of Medical Electronics and Biological Engineering. Vol. 22 Japan Soc of Medical Electronics & Biological Engineering, 1984. pp. 126-127
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abstract = "Augmented stroke volume (SV) accompanies an increase in ejection velocity (Ve). To determine whether Ve directly affects the LV relaxation rate irrespective of SV changes, the time constant (T) of isovolumic LV pressure (LVP) decay was studied in 8 isolated canine hearts. A water-filled balloon was inserted into LV cavity and instantaneous LV volume was controlled by servo-pump. To eliminate the effect of SV, end-systolic and end-diastolic volumes were clamped and LV was allowed to eject with 3-5 different velocities under two conditions; with mid-ejection time and with end of ejection unchanged. In any condition, T was not significantly altered by Ve changes. Thus, we conclude that LV relaxation rate is not influenced by ejection velocity. Enhanced LV relaxation rate in augmented SV may be due to the direct effect of the extent of muscle shortening.",
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AU - Hori, M.

AU - Ishida, Y.

AU - Fukunami, M.

AU - Kusuoka, H.

AU - Kigiya, T.

AU - Kitabatake, A.

AU - Inoue, M.

AU - Abe, H.

AU - Tsujioka, K.

AU - Nakajima, S.

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