Absence of deleterious palladin mutations in patients with familial pancreatic cancer

Alison P. Klein, Michael Borges, Margaret Griffith, Kieran Brune, Seung Mo Hong, Noriyuki Omura, Ralph H. Hruban, Michael Goggins

Research output: Contribution to journalArticle

Abstract

It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutations and find no evidence to implicate mutations in PALLD as a cause of familial pancreatic cancer.

Original languageEnglish (US)
Pages (from-to)1328-1330
Number of pages3
JournalCancer Epidemiology Biomarkers and Prevention
Volume18
Issue number4
DOIs
StatePublished - Apr 2009

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

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