Abolition of optokinetic afternystagmus by aminoglycoside ototoxicity

Timothy C. Hain; David S. Zee

doi:10.1177/000348949110000712

Abolition of optokinetic afternystagmus by aminoglycoside ototoxicity

Timothy C. Hain, David S. Zee

School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We studied optokinetic afternystagmus in eight subjects with loss of or impairment of vestibular function due to ototoxic antibiotics. We found that the initial amplitude, the time constant, and the slow-phase cumulative eye position of optokinetic afternystagmus were significantly reduced in the patients. Slow-phase cumulative eye position most reliably distinguished our patients' responses from those of a normal group.

Original language	English (US)
Pages (from-to)	580-583
Number of pages	4
Journal	Annals of Otology, Rhinology & Laryngology
Volume	100
Issue number	7
DOIs	https://doi.org/10.1177/000348949110000712
State	Published - Jul 1991

Keywords

optokinetic afternystagmus
ototoxicity
vestibular function

ASJC Scopus subject areas

Otorhinolaryngology

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10.1177/000348949110000712

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abstract = "We studied optokinetic afternystagmus in eight subjects with loss of or impairment of vestibular function due to ototoxic antibiotics. We found that the initial amplitude, the time constant, and the slow-phase cumulative eye position of optokinetic afternystagmus were significantly reduced in the patients. Slow-phase cumulative eye position most reliably distinguished our patients' responses from those of a normal group.",

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AB - We studied optokinetic afternystagmus in eight subjects with loss of or impairment of vestibular function due to ototoxic antibiotics. We found that the initial amplitude, the time constant, and the slow-phase cumulative eye position of optokinetic afternystagmus were significantly reduced in the patients. Slow-phase cumulative eye position most reliably distinguished our patients' responses from those of a normal group.

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KW - ototoxicity

KW - vestibular function

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Abolition of optokinetic afternystagmus by aminoglycoside ototoxicity

Abstract

Keywords

ASJC Scopus subject areas

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