Abstract
Background: Abnormal heart rate (HR) recovery at 1 min after exercise (≤12 beats) was recently suggested to be a predictor of all cause and cardiac mortality. Aim: This study aimed to (1) correlate HR recovery at 1 min after exercise with known exercise and myocardial perfusion markers of increased cardiac mortality, and (2) compare the known exercise and myocardial perfusion markers of increased cardiac mortality between patients with a normal and abnormal HR recovery at 1 min after exercise. Methods: One hundred patients with known or suspected coronary artery disease referred for exercise stress testing (ETT) were prospectively enrolled. Percent, ETT time peak HR, HR reserve, summed stress score (SSS), extent of stress (SE%) and reversible perfusion abnormalities (RE%) were recorded in every patient. Results: There was poor correlation with markers of myocardial ischemia or infarction [SSS (r = 0.15), SE% (r = 0.05), RE% (r = 0.12), all p = n.s.] but highly significant correlation between HR recovery at 1 min after exercise and chronotropic variables [ETT time (r = 0.56), peak HR (r = 0.65), HR reserve % (r = 0.64), all p <0.001]. Patients on β-blockers had significantly more incidence of an abnormal HR recovery at 1 min after exercise, compared to patients not on β-blockers (88 vs. 56%, p <0.01).Conclusion: Abnormal HR recovery at 1 min after exercise has no correlation with known myocardial perfusion markers of increased cardiac mortality. Patients with an abnormal HR recovery do not appear to have an increased incidence or more severe myocardial infarction or ischemia. However, there is a strong correlation between HR recovery at 1 min after exercise and the chronotropic variables during exercise.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 38-44 |
| Number of pages | 7 |
| Journal | Cardiology |
| Volume | 96 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2001 |
| Externally published | Yes |
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Keywords
- Exercise electrocardiography
- Heart rate recovery
- Single photon emission computed tomography
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Abnormal heart rate recovery after exercise : A comparison with known indicators of increased mortality. / Desai, Milind Y.; De La Peña-Almaguer, Erasmo; Mannting, Finn.
In: Cardiology, Vol. 96, No. 1, 2001, p. 38-44.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Abnormal heart rate recovery after exercise
T2 - A comparison with known indicators of increased mortality
AU - Desai, Milind Y.
AU - De La Peña-Almaguer, Erasmo
AU - Mannting, Finn
PY - 2001
Y1 - 2001
N2 - Background: Abnormal heart rate (HR) recovery at 1 min after exercise (≤12 beats) was recently suggested to be a predictor of all cause and cardiac mortality. Aim: This study aimed to (1) correlate HR recovery at 1 min after exercise with known exercise and myocardial perfusion markers of increased cardiac mortality, and (2) compare the known exercise and myocardial perfusion markers of increased cardiac mortality between patients with a normal and abnormal HR recovery at 1 min after exercise. Methods: One hundred patients with known or suspected coronary artery disease referred for exercise stress testing (ETT) were prospectively enrolled. Percent, ETT time peak HR, HR reserve, summed stress score (SSS), extent of stress (SE%) and reversible perfusion abnormalities (RE%) were recorded in every patient. Results: There was poor correlation with markers of myocardial ischemia or infarction [SSS (r = 0.15), SE% (r = 0.05), RE% (r = 0.12), all p = n.s.] but highly significant correlation between HR recovery at 1 min after exercise and chronotropic variables [ETT time (r = 0.56), peak HR (r = 0.65), HR reserve % (r = 0.64), all p <0.001]. Patients on β-blockers had significantly more incidence of an abnormal HR recovery at 1 min after exercise, compared to patients not on β-blockers (88 vs. 56%, p <0.01).Conclusion: Abnormal HR recovery at 1 min after exercise has no correlation with known myocardial perfusion markers of increased cardiac mortality. Patients with an abnormal HR recovery do not appear to have an increased incidence or more severe myocardial infarction or ischemia. However, there is a strong correlation between HR recovery at 1 min after exercise and the chronotropic variables during exercise.
AB - Background: Abnormal heart rate (HR) recovery at 1 min after exercise (≤12 beats) was recently suggested to be a predictor of all cause and cardiac mortality. Aim: This study aimed to (1) correlate HR recovery at 1 min after exercise with known exercise and myocardial perfusion markers of increased cardiac mortality, and (2) compare the known exercise and myocardial perfusion markers of increased cardiac mortality between patients with a normal and abnormal HR recovery at 1 min after exercise. Methods: One hundred patients with known or suspected coronary artery disease referred for exercise stress testing (ETT) were prospectively enrolled. Percent, ETT time peak HR, HR reserve, summed stress score (SSS), extent of stress (SE%) and reversible perfusion abnormalities (RE%) were recorded in every patient. Results: There was poor correlation with markers of myocardial ischemia or infarction [SSS (r = 0.15), SE% (r = 0.05), RE% (r = 0.12), all p = n.s.] but highly significant correlation between HR recovery at 1 min after exercise and chronotropic variables [ETT time (r = 0.56), peak HR (r = 0.65), HR reserve % (r = 0.64), all p <0.001]. Patients on β-blockers had significantly more incidence of an abnormal HR recovery at 1 min after exercise, compared to patients not on β-blockers (88 vs. 56%, p <0.01).Conclusion: Abnormal HR recovery at 1 min after exercise has no correlation with known myocardial perfusion markers of increased cardiac mortality. Patients with an abnormal HR recovery do not appear to have an increased incidence or more severe myocardial infarction or ischemia. However, there is a strong correlation between HR recovery at 1 min after exercise and the chronotropic variables during exercise.
KW - Exercise electrocardiography
KW - Heart rate recovery
KW - Single photon emission computed tomography
UR - http://www.scopus.com/inward/record.url?scp=0034766828&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034766828&partnerID=8YFLogxK
U2 - 10.1159/000047384
DO - 10.1159/000047384
M3 - Article
C2 - 11701939
AN - SCOPUS:0034766828
VL - 96
SP - 38
EP - 44
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 1
ER -