TY - JOUR
T1 - Abnormal Foveal Avascular Zone in Nanophthalmos
AU - Walsh, Mark K.
AU - Goldberg, Morton F.
N1 - Funding Information:
This study was supported by the Guerrieri Retinal Research Fund and the James T. Handa Research Award from the Wilmer Ophthalmological Institute, Baltimore, Maryland. The authors indicate no conflict of interest. Both authors were involved in design and conduct of study; collection, analysis and interpretation; and preparation of manuscript, review, and approval of the manuscript.
PY - 2007/6
Y1 - 2007/6
N2 - Purpose: To evaluate the foveas of nanophthalmic patients. Design: Retrospective observational case series. Methods: Four nanophthalmic patients examined between April 2005 and April 2006 were included. Visual acuity (VA), refractive correction, axial length, corneal diameter, presence or lack of foveal light reflex, as well as fluorescein angiograms (FAs), and optical coherence tomography (OCT) scans of the maculae were evaluated. Results: None of the eight eyes had a foveal light reflex, corresponding to lack of a normal foveal pit on OCT. Fluorescein angiography showed no normal foveal avascular zones; all were either completely absent or small and rudimentary. Conclusions: Nanophthalmic patients rarely have best-corrected visual acuity (BCVA) better than 20/40 at any point in their lives, even with an absence of known complications, such as uveal effusion or glaucoma. In many patients, this visual deficiency may correspond to an absent or rudimentary foveal avascular zone and lack of a normal foveal pit.
AB - Purpose: To evaluate the foveas of nanophthalmic patients. Design: Retrospective observational case series. Methods: Four nanophthalmic patients examined between April 2005 and April 2006 were included. Visual acuity (VA), refractive correction, axial length, corneal diameter, presence or lack of foveal light reflex, as well as fluorescein angiograms (FAs), and optical coherence tomography (OCT) scans of the maculae were evaluated. Results: None of the eight eyes had a foveal light reflex, corresponding to lack of a normal foveal pit on OCT. Fluorescein angiography showed no normal foveal avascular zones; all were either completely absent or small and rudimentary. Conclusions: Nanophthalmic patients rarely have best-corrected visual acuity (BCVA) better than 20/40 at any point in their lives, even with an absence of known complications, such as uveal effusion or glaucoma. In many patients, this visual deficiency may correspond to an absent or rudimentary foveal avascular zone and lack of a normal foveal pit.
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U2 - 10.1016/j.ajo.2007.01.051
DO - 10.1016/j.ajo.2007.01.051
M3 - Article
C2 - 17524786
AN - SCOPUS:34248591370
SN - 0002-9394
VL - 143
SP - 1067-1068.e2
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 6
ER -